MeSH Browser

MeSH Heading: Sterol O-Acyltransferase
Tree Number(s): D08.811.913.050.799
Unique ID: D002785
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D002785
Scope Note: An enzyme that catalyzes the formation of cholesterol esters by the direct transfer of the fatty acid group from a fatty acyl CoA derivative. This enzyme has been found in the adrenal gland, gonads, liver, intestinal mucosa, and aorta of many mammalian species. EC 2.3.1.26.
Entry Term(s): Acyl-CoA-Cholesterol Acyltransferase; Cholesterol Acyltransferase; Cholesterol Esterifying Enzyme
Registry Number: EC 2.3.1.26
Related Numbers: 9027-63-8
CAS Type 1 Name: Acyl-CoA:cholesterol O-acyltransferase
Previous Indexing: Acyltransferases (1973-1975); Cholesterol (1973-1975); Coenzyme A (1973-1975)
Public MeSH Note: 98; see CHOLESTEROL ACYLTRANSFERASE 1985-97; see ACYLTRANSFERASES 1976-84
History Note: 98(76)
Date Established: 1985/01/01
Date of Entry: 1975/07/25
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0004270
Registry Number: EC 2.3.1.26
Related Numbers: 9027-63-8
Scope Note: An enzyme that catalyzes the formation of cholesterol esters by the direct transfer of the fatty acid group from a fatty acyl CoA derivative. This enzyme has been found in the adrenal gland, gonads, liver, intestinal mucosa, and aorta of many mammalian species. EC 2.3.1.26.
Terms: Sterol O-Acyltransferase Preferred Term
Term UI T008083
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1976); Cholesterol Esterifying Enzyme
Term UI T008082
Date10/23/1981
LexicalTag NON
ThesaurusID UNK (19XX); Acyl-CoA-Cholesterol Acyltransferase
Term UI T008080
Date04/16/1984
LexicalTag NON
ThesaurusID UNK (19XX); Cholesterol Acyltransferase
Term UI T008081
Date12/03/1996
LexicalTag NON
ThesaurusID NLM (1998)

Sterol O-Acyltransferase MeSH Descriptor Data 2023