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Electron Transport Complex IV MeSH Descriptor Data 2023


MeSH Heading
Electron Transport Complex IV
Tree Number(s)
D05.500.562.374
D08.811.600.250.687
D08.811.682.285
D12.776.157.530.450.250.875.304
D12.776.543.277.687
D12.776.543.585.450.250.875.484
Unique ID
D003576
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003576
Annotation
spell in titles & translations with lowercase c: cytochrome-c oxidase
Scope Note
A multisubunit enzyme complex containing CYTOCHROME A GROUP; CYTOCHROME A3; two copper atoms; and 13 different protein subunits. It is the terminal oxidase complex of the RESPIRATORY CHAIN and collects electrons that are transferred from the reduced CYTOCHROME C GROUP and donates them to molecular OXYGEN, which is then reduced to water. The redox reaction is simultaneously coupled to the transport of PROTONS across the inner mitochondrial membrane.
Entry Term(s)
Cytochrome Oxidase
Cytochrome Oxidase Subunit III
Cytochrome a,a3
Cytochrome aa3
Cytochrome c Oxidase Subunit VIa
Cytochrome-c Oxidase
Cytochrome-c Oxidase (Complex IV)
Cytochrome-c Oxidase Subunit III
Cytochrome-c Oxidase Subunit IV
Ferrocytochrome c Oxygen Oxidoreductase
Heme aa3 Cytochrome Oxidase
Pre-CTOX p25
Signal Peptide p25-Subunit IV Cytochrome Oxidase
Subunit III, Cytochrome Oxidase
p25 Presequence Peptide-Cytochrome Oxidase
Registry Number
EC 1.9.3.1
Related Numbers
EC 1.9.3.1
CAS Type 1 Name
Ferricytochrome-c:oxygen oxidoreductase
NLM Classification #
QU 140
See Also
Cytochrome-c Oxidase Deficiency
Public MeSH Note
2004; see CYTOCHROME-C OXIDASE 1994-2003, see CYTOCHROME C OXIDASE 1992-1993, see CYTOCHROME OXIDASE 1963-1991; for CYTOCHROME C OXIDASE see CYTOCHROME OXIDASE 1984-1991; SIGNAL PEPTIDE P25-SUBUNIT IV CYTOCHROME OXIDASE was indexed under CYTOCHROME C OXIDASE 1988-2001; CYTOCHROME OXIDASE SUBUNIT III was indexed under CYTOCHROME C OXIDASE 1998-2001
History Note
2004(1963); for SIGNAL PEPTIDE P25-SUBUNIT IV CYTOCHROME OXIDASE use CYTOCHROME C OXIDASE (NM) 1988-2001; for CYTOCHROME OXIDASE SUBUNIT III use CYTOCHROME C OXIDASE (NM) 1998-2001
Entry Combination
deficiency:Cytochrome-c Oxidase Deficiency
Date Established
2004/01/01
Date of Entry
1999/01/01
Revision Date
2013/07/09
Electron Transport Complex IV Preferred
Signal Peptide p25-Subunit IV Cytochrome Oxidase Narrower
Cytochrome-c Oxidase Subunit III Narrower
Cytochrome-c Oxidase Subunit IV Narrower
Cytochrome aa3 Narrower
Cytochrome c Oxidase Subunit VIa Narrower
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