MeSH Browser

MeSH Heading: Proton Pumps
Tree Number(s): D12.776.157.530.450.250.875; D12.776.543.585.450.250.875
Unique ID: D017494
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017494
Annotation: /antag - consider also POTASSIUM HYDROGEN ATPASE /‌antag
Scope Note: Integral membrane proteins that transport protons across a membrane. This transport can be linked to the hydrolysis of ADENOSINE TRIPHOSPHATE. What is referred to as proton pump inhibitors frequently is about POTASSIUM HYDROGEN ATPASE.
Entry Term(s): H(+) Pump; H+ Pump; Proton Pump
Previous Indexing: Proton-Translocating ATPases (1984-1992)
Public MeSH Note: 2002; see PROTON PUMP 1993-2001
History Note: 2002(1993)
Entry Combination: antagonists & inhibitors:Proton Pump Inhibitors
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2013/07/08

Entry Combination: antagonists & inhibitors:Proton Pump Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Pumps [D12.776.157.530.450]
        
        Cation Transport Proteins [D12.776.157.530.450.250]
        
        Arsenite Transporting ATPases [D12.776.157.530.450.250.249]
        
        Calcium-Transporting ATPases [D12.776.157.530.450.250.500]
        
        Copper Transport Proteins [D12.776.157.530.450.250.578]
        
        Ferroportin [D12.776.157.530.450.250.695]
        
        Organic Cation Transport Proteins [D12.776.157.530.450.250.812]
        
        Proton Pumps [D12.776.157.530.450.250.875]
        
        Bacteriorhodopsins [D12.776.157.530.450.250.875.249]
        
        Electron Transport Complex I [D12.776.157.530.450.250.875.300]
        
        Electron Transport Complex III [D12.776.157.530.450.250.875.303]
        
        Electron Transport Complex IV [D12.776.157.530.450.250.875.304]
        
        Inorganic Pyrophosphatase [D12.776.157.530.450.250.875.487]
        
        Photosystem I Protein Complex [D12.776.157.530.450.250.875.492]
        
        Proton-Translocating ATPases [D12.776.157.530.450.250.875.500]
        
        Sodium Sulfate Cotransporter [D12.776.157.530.450.250.878]
        
        Sodium-Potassium-Exchanging ATPase [D12.776.157.530.450.250.880]
        
        Solute Carrier Family 12 [D12.776.157.530.450.250.910]
        
        Zinc Transporter 8 [D12.776.157.530.450.250.940]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Pumps [D12.776.543.585.450]
        
        Cation Transport Proteins [D12.776.543.585.450.250]
        
        Arsenite Transporting ATPases [D12.776.543.585.450.250.249]
        
        Calcium-Transporting ATPases [D12.776.543.585.450.250.500]
        
        Copper Transport Proteins [D12.776.543.585.450.250.578]
        
        Organic Cation Transport Proteins [D12.776.543.585.450.250.812]
        
        Proton Pumps [D12.776.543.585.450.250.875]
        
        Bacteriorhodopsins [D12.776.543.585.450.250.875.249]
        
        Cytochrome b6f Complex [D12.776.543.585.450.250.875.311]
        
        Electron Transport Complex I [D12.776.543.585.450.250.875.437]
        
        Electron Transport Complex III [D12.776.543.585.450.250.875.468]
        
        Electron Transport Complex IV [D12.776.543.585.450.250.875.484]
        
        Inorganic Pyrophosphatase [D12.776.543.585.450.250.875.487]
        
        Photosystem I Protein Complex [D12.776.543.585.450.250.875.492]
        
        Proton-Translocating ATPases [D12.776.543.585.450.250.875.500]
        
        Sodium Sulfate Cotransporter [D12.776.543.585.450.250.883]
        
        Sodium-Potassium-Exchanging ATPase [D12.776.543.585.450.250.890]
        
        Solute Carrier Family 12 [D12.776.543.585.450.250.918]
        
        Zinc Transporter 8 [D12.776.543.585.450.250.945]

Proton Pumps Preferred

Concept UI: M0026545
Scope Note: Integral membrane proteins that transport protons across a membrane. This transport can be linked to the hydrolysis of ADENOSINE TRIPHOSPHATE. What is referred to as proton pump inhibitors frequently is about POTASSIUM HYDROGEN ATPASE.
Terms: Proton Pumps Preferred Term
Term UI T431532
Date12/21/2000
LexicalTag NON
ThesaurusID NLM (2002); H(+) Pump
Term UI T052511
Date04/06/1992
LexicalTag NON
ThesaurusID NLM (1993); H+ Pump
Term UI T052510
Date02/11/1993
LexicalTag NON
ThesaurusID NLM (1994); Proton Pump
Term UI T052512
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1993)

Proton Pumps MeSH Descriptor Data 2025