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Mechlorethamine MeSH Descriptor Data 2022


MeSH Heading
Mechlorethamine
Tree Number(s)
D02.455.526.728.650.529
Unique ID
D008466
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D008466
Scope Note
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.
Entry Term(s)
Bis(2-chloroethyl)methylamine
Caryolysine
Chlorethazine
Chlormethine
Cloramin
Embichin
Mechlorethamine Hydrochloride
Mechlorethamine Hydrochloride N-Oxide
Mechlorethamine N-Oxide
Mechlorethamine Oxide
Methylchlorethamine
Mitomen
Mustargen
Mustine
NSC-10107
NSC-762
Nitrogen Mustard
Nitrogen Mustard N-Oxide
Nitrogranulogen
Nitromin
Pharm Action
Alkylating Agents
Chemical Warfare Agents
Irritants
Antineoplastic Agents, Alkylating
Registry Number
50D9XSG0VR
Related Numbers
126-85-2
302-70-5
51-75-2
55-86-7
L0MR697HHI
CAS Type 1 Name
Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-
NLM Classification #
QV 269
Public MeSH Note
MECHLORETHAMINE OXIDE was heading 1963-79; NITROGEN MUSTARD N-OXIDE was indexed under NITROGEN MUSTARD COMPOUNDS 1984-91
Online Note
use MECHLORETHAMINE to search MECHLORETHAMINE OXIDE 1966-79; use MECHLORETHAMINE (NM) to search NITROGEN MUSTARD N-OXIDE (NM) 1984-91
History Note
MECHLORETHAMINE OXIDE was heading 1963-79; NITROGEN MUSTARD N-OXIDE was NITROGEN MUSTARD N-OXIDE (NM) 1984-91
Date Established
1963/01/01
Date of Entry
1999/01/01
Revision Date
2016/07/01
Mechlorethamine Preferred
Cloramin Narrower
Embichin Narrower
Mechlorethamine Hydrochloride Narrower
Mechlorethamine Hydrochloride N-Oxide Narrower
NSC-762 Narrower
Mechlorethamine Oxide Narrower
Mitomen Narrower
Mustargen Narrower
Nitrogranulogen Narrower
Nitromin Narrower
NSC-10107 Narrower
Caryolysine Narrower
Mechlorethamine N-Oxide Narrower
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