MeSH Browser

MeSH Heading: Oxyphenonium
Tree Number(s): D02.092.877.648; D02.675.276.648
Unique ID: D010115
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010115
Scope Note: A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of ATROPINE. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect.
Entry Term(s): 2-((Cyclohexylhydroxyphenylacetyl)oxy)-N,N-diethyl-N-methylethanaminium; Atrenyl; Metacin; Methacin; Oxyphenon; Oxyphenonium Bromide; Oxyphenonium Bromide, (+)-Isomer; Oxyphenonium Bromide, (+-)-Isomer; Oxyphenonium Bromide, (-)-Isomer; Oxyphenonium Chloride; Oxyphenonium Iodide; Oxyphenonium Iodide, (R)-Isomer; Oxyphenonium Iodide, (S)-Isomer; Oxyphenonium, (+-)-Isomer; Oxyphenonium, (R)-Isomer; Oxyphenonium, (S)-Isomer; Spastrex
Pharm Action: Mydriatics
Parasympatholytics
Muscarinic Antagonists
Related Numbers: 108940-72-3; 14214-84-7; 25423-35-2; 3521-80-0,; 50-10-2; 50699-98-4; 50895-90-4; 58875-49-3; 99102-05-3; 99102-06-4; 99545-99-0; 99553-51-2; S9421HWB3Z
CAS Type 1 Name: Ethanaminium, 2-((cyclohexylhydroxyphenylacetyl)oxy)-N,N-diethyl-N-methyl-
Previous Indexing: Oxyphenonium Bromide (1966-1991)
Public MeSH Note: 92; was OXYPHENONIUM BROMIDE 1964-91 (see under AMMONIUM COMPOUNDS 1964-90)
Online Note: use OXYPHENONIUM to search OXYPHENONIUM BROMIDE 1966-91
History Note: 92(64); was OXYPHENONIUM BROMIDE 1964-91 (see under AMMONIUM COMPOUNDS 1964-90)
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Organic Chemicals [D02]
- Amines [D02.092]
  - Quaternary Ammonium Compounds [D02.092.877]

Organic Chemicals [D02]
- Onium Compounds [D02.675]
  - Quaternary Ammonium Compounds [D02.675.276]

Oxyphenonium Preferred

Concept UI: M0015691
Related Numbers: 108940-72-3; 14214-84-7; 25423-35-2; 3521-80-0,; 50-10-2; 50699-98-4; 50895-90-4; 58875-49-3; 99102-05-3; 99102-06-4; 99545-99-0; 99553-51-2; S9421HWB3Z
Scope Note: A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of ATROPINE. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect.
Terms: Oxyphenonium Preferred Term
Term UI T029922
Date01/01/1999
LexicalTag NON
ThesaurusID; Oxyphenon
Term UI T029925
Date11/18/1986
LexicalTag NON
ThesaurusID UNK (19XX); Methacin
Term UI T029921
Date07/13/1981
LexicalTag NON
ThesaurusID UNK (19XX); 2-((Cyclohexylhydroxyphenylacetyl)oxy)-N,N-diethyl-N-methylethanaminium
Term UI T029923
Date03/23/1994
LexicalTag NON
ThesaurusID NLM (1995); Metacin
Term UI T029924
Date07/13/1981
LexicalTag NON
ThesaurusID UNK (19XX)

Oxyphenonium Bromide Narrower

Oxyphenonium Chloride Narrower

Oxyphenonium Iodide Narrower

Spastrex Narrower

Oxyphenonium Bromide, (+-)-Isomer Narrower

Oxyphenonium Iodide, (R)-Isomer Narrower

Oxyphenonium Iodide, (S)-Isomer Narrower

Oxyphenonium, (+-)-Isomer Related

Oxyphenonium Bromide, (+)-Isomer Narrower

Oxyphenonium Bromide, (-)-Isomer Narrower

Oxyphenonium, (R)-Isomer Related

Oxyphenonium, (S)-Isomer Related

Atrenyl Narrower

Oxyphenonium MeSH Descriptor Data 2025