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Paralyses, Familial Periodic MeSH Descriptor Data 2023


MeSH Heading
Paralyses, Familial Periodic
Tree Number(s)
C05.651.701
C10.668.491.650
C16.320.565.618.711
C18.452.648.618.711
Unique ID
D010245
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010245
Annotation
a specific disease entity: see MeSH definition
Scope Note
A heterogenous group of inherited disorders characterized by recurring attacks of rapidly progressive flaccid paralysis or myotonia. These conditions have in common a mutation of the gene encoding the alpha subunit of the sodium channel in skeletal muscle. They are frequently associated with fluctuations in serum potassium levels. Periodic paralysis may also occur as a non-familial process secondary to THYROTOXICOSIS and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1481)
Entry Term(s)
Familial Periodic Paralysis
Normokalemic Periodic Paralysis
Periodic Paralysis, Familial
Public MeSH Note
2000; see PARALYSIS, FAMILIAL PERIODIC 1966-1999
History Note
2000(1966)
Date Established
2000/01/01
Date of Entry
1999/01/01
Revision Date
2012/07/03
Paralyses, Familial Periodic Preferred
Normokalemic Periodic Paralysis Narrower
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