MeSH Browser

MeSH Heading: Peptichemio
Tree Number(s): D02.455.526.728.650.594.690; D12.644.456.726
Unique ID: D010440
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010440
Scope Note: A mixture of six synthetic oligopeptides, each containing MELPHALAN. It is used as a broad-spectrum antineoplastic due to its alkylating and antimetabolic actions but, is toxic to bone marrow, gastrointestinal system and vasculature.
Pharm Action: Antimetabolites, Antineoplastic
Antineoplastic Agents, Alkylating
CAS Type 1 Name: Peptichemio
Previous Indexing: Nitrogen Mustard Compounds (1974); Peptides (1974)
Public MeSH Note: 91; was see under MELPHALAN 1981-90; was see under NITROGEN MUSTARD COMPOUNDS 1975-80
History Note: 91(75); was see under MELPHALAN 1981-90; was see under NITROGEN MUSTARD COMPOUNDS 1975-80
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2000/06/22

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Peptichemio MeSH Descriptor Data 2025