MeSH Browser

MeSH Heading: Deoxyribonucleases, Type II Site-Specific
Tree Number(s): D08.811.150.280.260; D08.811.277.352.335.350.300.260; D08.811.277.352.355.325.300.260
Unique ID: D015252
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015252
Scope Note: Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are separate enzymes. The systems recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.4.
Entry Version: DNASE SS II
Entry Term(s): DNA Restriction Enzymes, Type II; DNase, Site Specific, Type II; DNase, Site-Specific, Type II; Deoxyribonucleases, Type II, Site Specific; Deoxyribonucleases, Type II, Site-Specific; Restriction Endonucleases, Type II; Site-Specific DNase, Type II; Type II Restriction Enzymes; Type II Site Specific DNase; Type II Site Specific Deoxyribonucleases; Type II Site-Specific DNase; Type II Site-Specific Deoxyribonucleases
Registry Numbers: EC 3.1.21.4
Previous Indexing: DNA Restriction Enzymes (1978-1988)
Public MeSH Note: 89
History Note: 89
Date Established: 1989/01/01
Date of Entry: 1988/05/17
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - DNA Restriction-Modification Enzymes [D08.811.150]
    - DNA Restriction Enzymes [D08.811.150.280]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Deoxyribonucleases [D08.811.277.352.335]
        
        Endodeoxyribonucleases [D08.811.277.352.335.350]
        
        DNA Restriction Enzymes [D08.811.277.352.335.350.300]
        
        Deoxyribonucleases, Type I Site-Specific [D08.811.277.352.335.350.300.250]
        
        Deoxyribonucleases, Type II Site-Specific [D08.811.277.352.335.350.300.260]
        
        Deoxyribonuclease BamHI [D08.811.277.352.335.350.300.260.240]
        
        Deoxyribonuclease EcoRI [D08.811.277.352.335.350.300.260.250]
        
        Deoxyribonuclease HindIII [D08.811.277.352.335.350.300.260.260]
        
        Deoxyribonuclease HpaII [D08.811.277.352.335.350.300.260.300]
        
        Deoxyribonucleases, Type III Site-Specific [D08.811.277.352.335.350.300.270]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Endonucleases [D08.811.277.352.355]
        
        Endodeoxyribonucleases [D08.811.277.352.355.325]
        
        DNA Restriction Enzymes [D08.811.277.352.355.325.300]
        
        Deoxyribonucleases, Type I Site-Specific [D08.811.277.352.355.325.300.250]
        
        Deoxyribonucleases, Type II Site-Specific [D08.811.277.352.355.325.300.260]
        
        Deoxyribonuclease BamHI [D08.811.277.352.355.325.300.260.240]
        
        Deoxyribonuclease EcoRI [D08.811.277.352.355.325.300.260.250]
        
        Deoxyribonuclease HindIII [D08.811.277.352.355.325.300.260.260]
        
        Deoxyribonuclease HpaII [D08.811.277.352.355.325.300.260.300]
        
        Deoxyribonucleases, Type III Site-Specific [D08.811.277.352.355.325.300.270]

Deoxyribonucleases, Type II Site-Specific Preferred

Concept UI: M0023490
Registry Numbers: EC 3.1.21.4
Scope Note: Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are separate enzymes. The systems recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.4.
Terms: Deoxyribonucleases, Type II Site-Specific Preferred Term
Term UI T044753
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1989); Deoxyribonucleases, Type II, Site-Specific
Term UI T044750
Date02/08/1989
LexicalTag NON
ThesaurusID NLM (1989); Type II Site Specific Deoxyribonucleases
Term UI T044751
Date02/08/1989
LexicalTag NON
ThesaurusID NLM (1989); Type II Site-Specific Deoxyribonucleases
Term UI T044752
Date05/17/1988
LexicalTag NON
ThesaurusID UNK (19XX); DNA Restriction Enzymes, Type II
Term UI T044754
Date05/17/1988
LexicalTag NON
ThesaurusID UNK (19XX); DNase, Site Specific, Type II
Term UI T044755
Date05/17/1988
LexicalTag NON
ThesaurusID UNK (19XX); Site-Specific DNase, Type II
Term UI T044756
Date05/17/1988
LexicalTag NON
ThesaurusID UNK (19XX); Type II Site Specific DNase
Term UI T044757
Date02/08/1989
LexicalTag NON
ThesaurusID NLM (1989); Type II Site-Specific DNase
Term UI T044758
Date05/17/1988
LexicalTag NON
ThesaurusID UNK (19XX); DNase, Site-Specific, Type II
Term UI T044759
Date05/17/1988
LexicalTag NON
ThesaurusID UNK (19XX); Restriction Endonucleases, Type II
Term UI T044760
Date05/17/1988
LexicalTag NON
ThesaurusID UNK (19XX); Deoxyribonucleases, Type II, Site Specific
Term UI T044749
Date05/17/1988
LexicalTag NON
ThesaurusID UNK (19XX); Type II Restriction Enzymes
Term UI T044761
Date05/17/1988
LexicalTag NON
ThesaurusID UNK (19XX)

Deoxyribonucleases, Type II Site-Specific MeSH Descriptor Data 2024