MeSH Browser

MeSH Heading: Deoxyribonucleases, Type III Site-Specific
Tree Number(s): D08.811.150.280.270; D08.811.277.352.335.350.300.270; D08.811.277.352.355.325.300.270
Unique ID: D015263
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015263
Scope Note: Enzyme systems composed of two subunits and requiring ATP and magnesium for endonucleolytic activity; they do not function as ATPases. They exist as complexes with modification methylases of similar specificity listed under EC 2.1.1.72 or EC 2.1.1.73. The systems recognize specific short DNA sequences and cleave a short distance, about 24 to 27 bases, away from the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.5.
Entry Version: DNASE SS III
Entry Term(s): DNA Restriction Enzymes, Type III; DNase, Site Specific, Type III; DNase, Site-Specific, Type III; Deoxyribonucleases, Type III, Site Specific; Deoxyribonucleases, Type III, Site-Specific; Restriction Endonucleases, Type III; Site-Specific DNase, Type III; Type III Restriction Enzymes; Type III Site Specific DNase; Type III Site Specific Deoxyribonucleases; Type III Site-Specific DNase; Type III Site-Specific Deoxyribonucleases
Registry Numbers: EC 3.1.21.5
Previous Indexing: DNA Restriction Enzymes (1975-1988)
Public MeSH Note: 89
History Note: 89
Date Established: 1989/01/01
Date of Entry: 1988/05/18
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - DNA Restriction-Modification Enzymes [D08.811.150]
    - DNA Restriction Enzymes [D08.811.150.280]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Deoxyribonucleases [D08.811.277.352.335]
        
        Endodeoxyribonucleases [D08.811.277.352.335.350]
        
        DNA Restriction Enzymes [D08.811.277.352.335.350.300]
        
        Deoxyribonucleases, Type I Site-Specific [D08.811.277.352.335.350.300.250]
        
        Deoxyribonucleases, Type II Site-Specific [D08.811.277.352.335.350.300.260]
        
        Deoxyribonucleases, Type III Site-Specific [D08.811.277.352.335.350.300.270]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Endonucleases [D08.811.277.352.355]
        
        Endodeoxyribonucleases [D08.811.277.352.355.325]
        
        DNA Restriction Enzymes [D08.811.277.352.355.325.300]
        
        Deoxyribonucleases, Type I Site-Specific [D08.811.277.352.355.325.300.250]
        
        Deoxyribonucleases, Type II Site-Specific [D08.811.277.352.355.325.300.260]
        
        Deoxyribonucleases, Type III Site-Specific [D08.811.277.352.355.325.300.270]

Deoxyribonucleases, Type III Site-Specific Preferred

Concept UI: M0023503
Registry Numbers: EC 3.1.21.5
Scope Note: Enzyme systems composed of two subunits and requiring ATP and magnesium for endonucleolytic activity; they do not function as ATPases. They exist as complexes with modification methylases of similar specificity listed under EC 2.1.1.72 or EC 2.1.1.73. The systems recognize specific short DNA sequences and cleave a short distance, about 24 to 27 bases, away from the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.5.
Terms: Deoxyribonucleases, Type III Site-Specific Preferred Term
Term UI T044831
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1989); Deoxyribonucleases, Type III, Site-Specific
Term UI T044828
Date02/08/1989
LexicalTag NON
ThesaurusID NLM (1989); Type III Site Specific Deoxyribonucleases
Term UI T044829
Date02/08/1989
LexicalTag NON
ThesaurusID NLM (1989); Type III Site-Specific Deoxyribonucleases
Term UI T044830
Date05/18/1988
LexicalTag NON
ThesaurusID UNK (19XX); DNA Restriction Enzymes, Type III
Term UI T044832
Date05/18/1988
LexicalTag NON
ThesaurusID UNK (19XX); DNase, Site Specific, Type III
Term UI T044833
Date05/18/1988
LexicalTag NON
ThesaurusID UNK (19XX); Site-Specific DNase, Type III
Term UI T044834
Date05/18/1988
LexicalTag NON
ThesaurusID UNK (19XX); Type III Site Specific DNase
Term UI T044835
Date02/08/1989
LexicalTag NON
ThesaurusID NLM (1989); Type III Site-Specific DNase
Term UI T044836
Date05/18/1988
LexicalTag NON
ThesaurusID UNK (19XX); DNase, Site-Specific, Type III
Term UI T044837
Date05/18/1988
LexicalTag NON
ThesaurusID UNK (19XX); Restriction Endonucleases, Type III
Term UI T044838
Date05/18/1988
LexicalTag NON
ThesaurusID UNK (19XX); Deoxyribonucleases, Type III, Site Specific
Term UI T044827
Date05/18/1988
LexicalTag NON
ThesaurusID UNK (19XX); Type III Restriction Enzymes
Term UI T044839
Date05/18/1988
LexicalTag NON
ThesaurusID UNK (19XX)

Deoxyribonucleases, Type III Site-Specific MeSH Descriptor Data 2024