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Metabolic Detoxication, Phase II MeSH Descriptor Data 2022


MeSH Heading
Metabolic Detoxication, Phase II
Tree Number(s)
G03.171.450.750
G03.787.225.450.750
G07.690.725.225.450.750
Unique ID
D050217
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050217
Scope Note
The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products.
Entry Version
METAB DETOX PHASE II
Entry Term(s)
Metabolic Detoxication, Conjugative
Metabolic Detoxification, Phase II
Phase II Detoxification
See Also
Antioxidant Response Elements
Protein Processing, Post-Translational
Public MeSH Note
2006
History Note
2006
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2016/06/30
Metabolic Detoxication, Phase II Preferred
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