MeSH Browser

MeSH Heading: Indoleamine-Pyrrole 2,3,-Dioxygenase
Tree Number(s): D08.811.682.690.416.333
Unique ID: D050503
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050503
Scope Note: A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is an extrahepatic enzyme that plays a role in metabolism as the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.
Entry Term(s): IDO Dioxygenase; Indolamine-2,3-Dioxygenase; Indoleamine 2,3-Dioxygenase; Indoleamine-Oxygen 2,3-Oxidoreductase (Decyclizing)
Previous Indexing: Dioxygenases (2005); Oxygenases (1970-2004); Tryptophan Oxygenase (1968-2005)
Public MeSH Note: 2006; see TRYPTOPHAN OXYGENASE 1990-2005; INDOLAMINE-2,3-DIOXYGENASE was indexed under DIOXYGENASES 2005 and OXYGENASES 1990-2004
History Note: 2006(1990)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2012/07/03

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0475654
Scope Note: A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is an extrahepatic enzyme that plays a role in metabolism as the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.
Terms: Indoleamine-Pyrrole 2,3,-Dioxygenase Preferred Term
Term UI T618510
Date11/19/2004
LexicalTag NON
ThesaurusID NLM (2006); IDO Dioxygenase
Term UI T618569
Date11/19/2004
LexicalTag ABX
ThesaurusID NLM (2006); Indolamine-2,3-Dioxygenase
Term UI T414432
Date05/16/2000
LexicalTag NON
ThesaurusID NLM (2006); Indoleamine 2,3-Dioxygenase
Term UI T042035
Date03/21/1989
LexicalTag NON
ThesaurusID NLM (1990); Indoleamine-Oxygen 2,3-Oxidoreductase (Decyclizing)
Term UI T042036
Date03/21/1989
LexicalTag NON
ThesaurusID NLM (1990)

Indoleamine-Pyrrole 2,3,-Dioxygenase MeSH Descriptor Data 2025