MeSH Browser

MeSH Heading: Cyclin-Dependent Kinase Inhibitor p15
Tree Number(s): D12.644.360.225.100; D12.776.167.187.100; D12.776.476.225.100; D12.776.624.776.355.100
Unique ID: D050762
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050762
Scope Note: An INK4 cyclin-dependent kinase inhibitor containing four ANKYRIN-LIKE REPEATS. INK4B is often inactivated by deletions, mutations, or hypermethylation in HEMATOLOGIC NEOPLASMS.
Entry Term(s): CDKN2B Protein; Cyclin-Dependent Kinase Inhibitor 2B; INK4B Protein; INK4b Cyclin-Dependent Kinase Inhibitor; p15 CDK4 Inhibitor; p15INK4B Protein
Pharm Action: Protein Kinase Inhibitors
Public MeSH Note: 2006; CYCLIN-DEPENDENT KINASE INHIBITOR P15 was indexed under TUMOR SUPPRESSOR PROTEINS & CELL CYCLE PROTEINS 2004-2005, under PROTEIN P16 2002-2004, & under CARRIER PROTEINS 1994-2001
History Note: 2006(1994)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0236014
Scope Note: An INK4 cyclin-dependent kinase inhibitor containing four ANKYRIN-LIKE REPEATS. INK4B is often inactivated by deletions, mutations, or hypermethylation in HEMATOLOGIC NEOPLASMS.
Terms: Cyclin-Dependent Kinase Inhibitor p15 Preferred Term
Term UI T623738
Date12/13/2004
LexicalTag NON
ThesaurusID NLM (2006); p15 CDK4 Inhibitor
Term UI T266016
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); INK4B Protein
Term UI T266019
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); CDKN2B Protein
Term UI T577337
Date03/16/2004
LexicalTag ABX
ThesaurusID NLM (2006); Cyclin-Dependent Kinase Inhibitor 2B
Term UI T623673
Date12/13/2004
LexicalTag NON
ThesaurusID NLM (2006); INK4b Cyclin-Dependent Kinase Inhibitor
Term UI T623674
Date12/13/2004
LexicalTag ABX
ThesaurusID NLM (2006); p15INK4B Protein
Term UI T623675
Date12/13/2004
LexicalTag ABX
ThesaurusID NLM (2006)

Cyclin-Dependent Kinase Inhibitor p15 MeSH Descriptor Data 2025