Focal Adhesion Kinase 2 MeSH Descriptor Data 2024

MeSH Heading: Focal Adhesion Kinase 2
Tree Number(s): D08.811.913.696.620.682.725.049.750; D12.776.476.568.049.750; D23.050.301.500.600.350; D23.050.705.552.600.350
Unique ID: D051418
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051418
Scope Note: A non-receptor protein-tyrosine kinase that is expressed primarily in the BRAIN; OSTEOBLASTS; and LYMPHOID CELLS. In the CENTRAL NERVOUS SYSTEM focal adhesion kinase 2 modulates ION CHANNEL function and MITOGEN-ACTIVATED PROTEIN KINASES activity.
Entry Term(s): CADTK Protein; Calcium-Dependent Protein Tyrosine Kinase; Cell Adhesion Kinase Beta; FAK Autokinase; Focal Adhesion Kinase Autokinase; PYK2 Protein Tyrosine Kinase; Proline-Rich Tyrosine Kinase 2; Protein Tyrosine Kinase PYK2; RAFTK Protein; Related Adhesion Focal Tyrosine Kinase
Registry Numbers: EC 2.7.10.2
Public MeSH Note: 2006; FOCAL ADHESION KINASE 2 was indexed under PROTEIN-TYROSINE KINASE 1995-2005
History Note: 2006(1995)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Transferases [D08.811.913]
    - Phosphotransferases [D08.811.913.696]
      - Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
        
        Protein Kinases [D08.811.913.696.620.682]
        
        Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
        
        Focal Adhesion Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.049]
        
        Focal Adhesion Kinase 1 [D08.811.913.696.620.682.725.049.500]
        
        Focal Adhesion Kinase 2 [D08.811.913.696.620.682.725.049.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Protein-Tyrosine Kinases [D12.776.476.568]
      - Focal Adhesion Protein-Tyrosine Kinases [D12.776.476.568.049]
        
        Focal Adhesion Kinase 1 [D12.776.476.568.049.500]
        
        Focal Adhesion Kinase 2 [D12.776.476.568.049.750]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Histocompatibility Antigens [D23.050.301.500]
      - Minor Histocompatibility Antigens [D23.050.301.500.600]
        
        Antigens, CD19 [D23.050.301.500.600.200]
        
        Cathepsin H [D23.050.301.500.600.300]
        
        Focal Adhesion Kinase 2 [D23.050.301.500.600.350]
        
        H-Y Antigen [D23.050.301.500.600.400]
        
        Receptor, ErbB-2 [D23.050.301.500.600.700]
        
        Receptors, Purinergic P2X5 [D23.050.301.500.600.775]
        
        Reduced Folate Carrier Protein [D23.050.301.500.600.813]
        
        rho Guanine Nucleotide Dissociation Inhibitor beta [D23.050.301.500.600.850]
        
        Thymidine Phosphorylase [D23.050.301.500.600.925]
        
        WNK Lysine-Deficient Protein Kinase 1 [D23.050.301.500.600.962]

Biological Factors [D23]
- Antigens [D23.050]
  - Isoantigens [D23.050.705]
    - Histocompatibility Antigens [D23.050.705.552]
      - Minor Histocompatibility Antigens [D23.050.705.552.600]
        
        Antigens, CD19 [D23.050.705.552.600.200]
        
        Cathepsin H [D23.050.705.552.600.300]
        
        Focal Adhesion Kinase 2 [D23.050.705.552.600.350]
        
        H-Y Antigen [D23.050.705.552.600.400]
        
        Receptor, ErbB-2 [D23.050.705.552.600.550]
        
        Receptors, Purinergic P2X5 [D23.050.705.552.600.625]
        
        Reduced Folate Carrier Protein [D23.050.705.552.600.663]
        
        rho Guanine Nucleotide Dissociation Inhibitor beta [D23.050.705.552.600.700]
        
        Thymidine Phosphorylase [D23.050.705.552.600.850]
        
        WNK Lysine-Deficient Protein Kinase 1 [D23.050.705.552.600.925]

Focal Adhesion Kinase 2 Preferred

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