Receptors, Purinergic P2X3 MeSH Descriptor Data 2023

MeSH Heading: Receptors, Purinergic P2X3
Tree Number(s): D12.776.157.530.400.400.750.300; D12.776.543.550.450.500.600.300; D12.776.543.585.400.500.600.300; D12.776.543.750.695.700.720.250.300; D12.776.543.750.720.700.720.500.300
Unique ID: D058477
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D058477
Scope Note: A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension, and NEUROPATHIC PAIN. The receptor comprises three P2X3 subunits. The P2X3 subunits are also associated with P2X2 RECEPTOR subunits in a heterotrimeric receptor variant.
Entry Term(s): P2X3 Purinoceptor; P2X3 Receptor; Purinergic Receptor P2X, Ligand-Gated Ion Channel, 3
Registry Number: 0
Public MeSH Note: 2011; PURINERGIC P2X3 RECEPTOR (now RECEPTORS, PURINERGIC P2X3) was indexed under RECEPTORS, PURINERGIC 1995-2010
History Note: 2011
Entry Combination: agonists:Purinergic P2X Receptor Agonists; antagonists & inhibitors:Purinergic P2X Receptor Antagonists
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Revision Date: 2016/07/01

Entry Combination: agonists:Purinergic P2X Receptor Agonists; antagonists & inhibitors:Purinergic P2X Receptor Antagonists
Allowable Qualifiers: administration & dosage (AD)

analysis (AN)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Channels [D12.776.157.530.400]
        
        Ligand-Gated Ion Channels [D12.776.157.530.400.400]
        
        Receptors, Purinergic P2X [D12.776.157.530.400.400.750]
        
        Receptors, Purinergic P2X1 [D12.776.157.530.400.400.750.100]
        
        Receptors, Purinergic P2X2 [D12.776.157.530.400.400.750.200]
        
        Receptors, Purinergic P2X3 [D12.776.157.530.400.400.750.300]
        
        Receptors, Purinergic P2X4 [D12.776.157.530.400.400.750.400]
        
        Receptors, Purinergic P2X5 [D12.776.157.530.400.400.750.500]
        
        Receptors, Purinergic P2X7 [D12.776.157.530.400.400.750.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Ion Channels [D12.776.543.550.450]
        
        Ligand-Gated Ion Channels [D12.776.543.550.450.500]
        
        Receptors, Purinergic P2X [D12.776.543.550.450.500.600]
        
        Receptors, Purinergic P2X1 [D12.776.543.550.450.500.600.100]
        
        Receptors, Purinergic P2X2 [D12.776.543.550.450.500.600.200]
        
        Receptors, Purinergic P2X3 [D12.776.543.550.450.500.600.300]
        
        Receptors, Purinergic P2X4 [D12.776.543.550.450.500.600.400]
        
        Receptors, Purinergic P2X5 [D12.776.543.550.450.500.600.500]
        
        Receptors, Purinergic P2X7 [D12.776.543.550.450.500.600.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Channels [D12.776.543.585.400]
        
        Ligand-Gated Ion Channels [D12.776.543.585.400.500]
        
        Receptors, Purinergic P2X [D12.776.543.585.400.500.600]
        
        Receptors, Purinergic P2X1 [D12.776.543.585.400.500.600.100]
        
        Receptors, Purinergic P2X2 [D12.776.543.585.400.500.600.200]
        
        Receptors, Purinergic P2X3 [D12.776.543.585.400.500.600.300]
        
        Receptors, Purinergic P2X4 [D12.776.543.585.400.500.600.400]
        
        Receptors, Purinergic P2X5 [D12.776.543.585.400.500.600.500]
        
        Receptors, Purinergic P2X7 [D12.776.543.585.400.500.600.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, G-Protein-Coupled [D12.776.543.750.695]
        
        Receptors, Purinergic [D12.776.543.750.695.700]
        
        Receptors, Purinergic P2 [D12.776.543.750.695.700.720]
        
        Receptors, Purinergic P2X [D12.776.543.750.695.700.720.250]
        
        Receptors, Purinergic P2X1 [D12.776.543.750.695.700.720.250.100]
        
        Receptors, Purinergic P2X2 [D12.776.543.750.695.700.720.250.200]
        
        Receptors, Purinergic P2X3 [D12.776.543.750.695.700.720.250.300]
        
        Receptors, Purinergic P2X4 [D12.776.543.750.695.700.720.250.400]
        
        Receptors, Purinergic P2X5 [D12.776.543.750.695.700.720.250.500]
        
        Receptors, Purinergic P2X7 [D12.776.543.750.695.700.720.250.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Neurotransmitter [D12.776.543.750.720]
        
        Receptors, Purinergic [D12.776.543.750.720.700]
        
        Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
        
        Receptors, Purinergic P2X [D12.776.543.750.720.700.720.500]
        
        Receptors, Purinergic P2X1 [D12.776.543.750.720.700.720.500.100]
        
        Receptors, Purinergic P2X2 [D12.776.543.750.720.700.720.500.200]
        
        Receptors, Purinergic P2X3 [D12.776.543.750.720.700.720.500.300]
        
        Receptors, Purinergic P2X4 [D12.776.543.750.720.700.720.500.400]
        
        Receptors, Purinergic P2X5 [D12.776.543.750.720.700.720.500.500]
        
        Receptors, Purinergic P2X7 [D12.776.543.750.720.700.720.500.700]

Receptors, Purinergic P2X3 Preferred

Concept UI: M0542732
Registry Number: 0
Scope Note: A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension, and NEUROPATHIC PAIN. The receptor comprises three P2X3 subunits. The P2X3 subunits are also associated with P2X2 RECEPTOR subunits in a heterotrimeric receptor variant.
Terms: Receptors, Purinergic P2X3 Preferred Term
Term UI T764263
Date01/15/2010
LexicalTag ABX
ThesaurusID NLM (2011); P2X3 Receptor
Term UI T764284
Date01/15/2010
LexicalTag ABX
ThesaurusID NLM (2011); Purinergic Receptor P2X, Ligand-Gated Ion Channel, 3
Term UI T764285
Date01/15/2010
LexicalTag ABX
ThesaurusID NLM (2011); P2X3 Purinoceptor
Term UI T764282
Date01/15/2010
LexicalTag ABX
ThesaurusID NLM (2011)

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