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Omalizumab MeSH Descriptor Data 2021


MeSH Heading
Omalizumab
Tree Number(s)
D12.776.124.486.485.114.071.500
D12.776.124.486.485.114.224.060.844
D12.776.124.790.651.114.071.500
D12.776.124.790.651.114.224.060.844
D12.776.377.715.548.114.071.500
D12.776.377.715.548.114.224.200.844
Unique ID
D000069444
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000069444
Scope Note
An anti-IgE, recombinant, humanized monoclonal antibody which specifically binds to the C epsilon3 domain of IMMUNOGLOBULIN E, the site of high-affinity IgE receptor binding. It inhibits the binding of IgE to MAST CELLS and BASOPHILS to reduce the severity of the allergic response and is used in the management of persistent allergic ASTHMA.
Entry Term(s)
Xolair
Pharm Action
Anti-Allergic Agents
Anti-Asthmatic Agents
Registry Number
2P471X1Z11
Related Numbers
242138-07-4
CAS Type 1 Name
Immunoglobulin G, anti-(human immunoglobulin E Fc region)(human-mouse monoclonal E25 clone pSVIE26 gamma-chain), disulfide with human-mouse monoclonal E25 clone pSVIE26 kappa-chain, dimer
NLM Classification #
QW 575.5.A6
Public MeSH Note
2016; OMALIZUMAB was indexed under ANTIBODIES, ANTI-IDIOTYPIC and ANTIBODIES, MONOCLONAL, HUMANIZED 2011-2015; and under ANTIBODIES, MONOCLONAL 2001-2011
History Note
2016 (2001)
Date Established
2016/01/01
Date of Entry
2015/07/01
Revision Date
2017/06/20
Omalizumab Preferred
Xolair Narrower
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