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Denosumab MeSH Descriptor Data 2023


MeSH Heading
Denosumab
Tree Number(s)
D12.776.124.486.485.114.224.060.782
D12.776.124.790.651.114.224.060.782
D12.776.377.715.548.114.224.200.782
Unique ID
D000069448
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000069448
Scope Note
A humanized monoclonal antibody and an inhibitor of the RANK LIGAND, which regulates OSTEOCLAST differentiation and bone remodeling. It is used as a BONE DENSITY CONSERVATION AGENT in the treatment of OSTEOPOROSIS.
Entry Term(s)
AMG 162
Prolia
Xgeva
Pharm Action
Bone Density Conservation Agents
Registry Number
4EQZ6YO2HI
Related Numbers
615258-40-7
See Also
RANK Ligand
Public MeSH Note
2016; DENOSUMAB was indexed under ANTIBODIES, MONOCLONAL, HUMANIZED 2012-2015; and under ANTIBODIES, MONOCLONAL 2004-2012
History Note
2016 (2004)
Date Established
2016/01/01
Date of Entry
2015/07/01
Revision Date
2017/06/20
Denosumab Preferred
Xgeva Narrower
AMG 162 Narrower
Prolia Narrower
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