MeSH Browser

MeSH Heading: Nivolumab
Tree Number(s): D12.776.124.486.485.114.224.060.829; D12.776.124.790.651.114.224.060.829; D12.776.377.715.548.114.224.200.829
Unique ID: D000077594
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077594
Scope Note: A genetically engineered, fully humanized immunoglobulin G4 monoclonal antibody that binds to the PD-1 RECEPTOR, activating an immune response to tumor cells. It is used as monotherapy or in combination with IPILIMUMAB for the treatment of advanced malignant MELANOMA. It is also used in the treatment of advanced or recurring NON-SMALL CELL LUNG CANCER; RENAL CELL CARCINOMA; and HODGKIN'S LYMPHOMA.
Entry Term(s): BMS-936558; MDX-1106; ONO-4538; Opdivo
Pharm Action: Antineoplastic Agents, Immunological
Immune Checkpoint Inhibitors
Registry Number: 31YO63LBSN
Public MeSH Note: 2019; NIVOLUMAB was indexed under ANTIBODIES, MONOCLONAL 2010-2018
History Note: 2019 (2010)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2020/02/28

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Immunoproteins [D12.776.124.486]
      - Immunoglobulins [D12.776.124.486.485]
        
        Antibodies [D12.776.124.486.485.114]
        
        Antibodies, Monoclonal [D12.776.124.486.485.114.224]
        
        Antibodies, Monoclonal, Humanized [D12.776.124.486.485.114.224.060]
        
        Abciximab [D12.776.124.486.485.114.224.060.125]
        
        Adalimumab [D12.776.124.486.485.114.224.060.250]
        
        Alemtuzumab [D12.776.124.486.485.114.224.060.313]
        
        Basiliximab [D12.776.124.486.485.114.224.060.344]
        
        Bevacizumab [D12.776.124.486.485.114.224.060.375]
        
        Brentuximab Vedotin [D12.776.124.486.485.114.224.060.438]
        
        Certolizumab Pegol [D12.776.124.486.485.114.224.060.500]
        
        Cetuximab [D12.776.124.486.485.114.224.060.750]
        
        Daclizumab [D12.776.124.486.485.114.224.060.766]
        
        Denosumab [D12.776.124.486.485.114.224.060.782]
        
        Gemtuzumab [D12.776.124.486.485.114.224.060.790]
        
        Inotuzumab Ozogamicin [D12.776.124.486.485.114.224.060.794]
        
        Ipilimumab [D12.776.124.486.485.114.224.060.798]
        
        Natalizumab [D12.776.124.486.485.114.224.060.813]
        
        Nivolumab [D12.776.124.486.485.114.224.060.829]
        
        Omalizumab [D12.776.124.486.485.114.224.060.844]
        
        Palivizumab [D12.776.124.486.485.114.224.060.860]
        
        Panitumumab [D12.776.124.486.485.114.224.060.864]
        
        Ranibizumab [D12.776.124.486.485.114.224.060.868]
        
        Trastuzumab [D12.776.124.486.485.114.224.060.875]
        
        Ustekinumab [D12.776.124.486.485.114.224.060.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Serum Globulins [D12.776.124.790]
      - Immunoglobulins [D12.776.124.790.651]
        
        Antibodies [D12.776.124.790.651.114]
        
        Antibodies, Monoclonal [D12.776.124.790.651.114.224]
        
        Antibodies, Monoclonal, Humanized [D12.776.124.790.651.114.224.060]
        
        Abciximab [D12.776.124.790.651.114.224.060.125]
        
        Adalimumab [D12.776.124.790.651.114.224.060.250]
        
        Alemtuzumab [D12.776.124.790.651.114.224.060.375]
        
        Basiliximab [D12.776.124.790.651.114.224.060.407]
        
        Bevacizumab [D12.776.124.790.651.114.224.060.438]
        
        Brentuximab Vedotin [D12.776.124.790.651.114.224.060.469]
        
        Certolizumab Pegol [D12.776.124.790.651.114.224.060.500]
        
        Cetuximab [D12.776.124.790.651.114.224.060.750]
        
        Daclizumab [D12.776.124.790.651.114.224.060.766]
        
        Denosumab [D12.776.124.790.651.114.224.060.782]
        
        Gemtuzumab [D12.776.124.790.651.114.224.060.790]
        
        Inotuzumab Ozogamicin [D12.776.124.790.651.114.224.060.794]
        
        Ipilimumab [D12.776.124.790.651.114.224.060.798]
        
        Natalizumab [D12.776.124.790.651.114.224.060.813]
        
        Nivolumab [D12.776.124.790.651.114.224.060.829]
        
        Omalizumab [D12.776.124.790.651.114.224.060.844]
        
        Palivizumab [D12.776.124.790.651.114.224.060.860]
        
        Panitumumab [D12.776.124.790.651.114.224.060.864]
        
        Ranibizumab [D12.776.124.790.651.114.224.060.868]
        
        Trastuzumab [D12.776.124.790.651.114.224.060.875]
        
        Ustekinumab [D12.776.124.790.651.114.224.060.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Globulins [D12.776.377]
    - Serum Globulins [D12.776.377.715]
      - Immunoglobulins [D12.776.377.715.548]
        
        Antibodies [D12.776.377.715.548.114]
        
        Antibodies, Monoclonal [D12.776.377.715.548.114.224]
        
        Antibodies, Monoclonal, Humanized [D12.776.377.715.548.114.224.200]
        
        Abciximab [D12.776.377.715.548.114.224.200.125]
        
        Adalimumab [D12.776.377.715.548.114.224.200.250]
        
        Alemtuzumab [D12.776.377.715.548.114.224.200.375]
        
        Basiliximab [D12.776.377.715.548.114.224.200.407]
        
        Bevacizumab [D12.776.377.715.548.114.224.200.438]
        
        Brentuximab Vedotin [D12.776.377.715.548.114.224.200.469]
        
        Certolizumab Pegol [D12.776.377.715.548.114.224.200.500]
        
        Cetuximab [D12.776.377.715.548.114.224.200.750]
        
        Daclizumab [D12.776.377.715.548.114.224.200.766]
        
        Denosumab [D12.776.377.715.548.114.224.200.782]
        
        Gemtuzumab [D12.776.377.715.548.114.224.200.790]
        
        Inotuzumab Ozogamicin [D12.776.377.715.548.114.224.200.794]
        
        Ipilimumab [D12.776.377.715.548.114.224.200.798]
        
        Natalizumab [D12.776.377.715.548.114.224.200.813]
        
        Nivolumab [D12.776.377.715.548.114.224.200.829]
        
        Omalizumab [D12.776.377.715.548.114.224.200.844]
        
        Palivizumab [D12.776.377.715.548.114.224.200.860]
        
        Panitumumab [D12.776.377.715.548.114.224.200.864]
        
        Ranibizumab [D12.776.377.715.548.114.224.200.868]
        
        Trastuzumab [D12.776.377.715.548.114.224.200.875]
        
        Ustekinumab [D12.776.377.715.548.114.224.200.937]

Nivolumab Preferred

Opdivo Narrower

ONO-4538 Narrower

MDX-1106 Narrower

BMS-936558 Narrower

Nivolumab MeSH Descriptor Data 2023