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Abatacept MeSH Descriptor Data 2021


MeSH Heading
Abatacept
Tree Number(s)
D12.776.124.790.651.114.580.225
D12.776.377.715.548.114.580.225
Unique ID
D000069594
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000069594
Scope Note
A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS.
Entry Term(s)
BMS 188667
BMS-188667
BMS-224818
BMS224818
Belatacept
CTLA-4-Ig
CTLA4-Fc
CTLA4-Ig
CTLA4-Ig Immunoconjugate
Cytotoxic T Lymphocyte-Associated Antigen 4-Immunoglobulin
LEA29Y
Nulojix
Orencia
Pharm Action
Immune Checkpoint Inhibitors
Immunosuppressive Agents
Antirheumatic Agents
Registry Number
7D0YB67S97
Related Numbers
332348-12-6
See Also
CTLA-4 Antigen
Public MeSH Note
2016; ABATACEPT was indexed under IMMUNOCONJUGATES 2002-2015
History Note
2016 (2002)
Date Established
2016/01/01
Date of Entry
2015/07/01
Revision Date
2020/02/28
Abatacept Preferred
CTLA-4-Ig Narrower
BMS224818 Narrower
Belatacept Narrower
Orencia Narrower
BMS 188667 Narrower
LEA29Y Narrower
Nulojix Narrower
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