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Simeprevir MeSH Descriptor Data 2023


MeSH Heading
Simeprevir
Tree Number(s)
D02.886.590.700.700
D03.633.300.819
Unique ID
D000069616
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000069616
Scope Note
Oral HCV-PROTEASE INHIBITOR effective against hepatitis C virus (HCV) serine protease NS3/4A. It is used in the treatment of chronic hepatitis C (Antivirals) genotype 1 infection in adults with compensated liver disease, including CIRRHOSIS.
Entry Term(s)
N-(17-(2-(4-isopropylthiazole-2-yl)-7-methoxy-8-methylquinolin-4-yloxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo(13.3.0.04,6)octadec-7-ene-4-carbonyl)(cyclopropyl)sulfonamide
Olysio
TMC 435
TMC 435350
TMC-435
TMC-435350
TMC435
TMC435350
Pharm Action
Antiviral Agents
Protease Inhibitors
Registry Number
9WS5RD66HZ
Public MeSH Note
2016; SIMEPREVIR was indexed under SULFONAMIDES and HETEROCYCLIC COMPOUNDS, 3-RING 2008-2015
History Note
2016 (2008)
Date Established
2016/01/01
Date of Entry
2015/07/10
Revision Date
2016/05/31
Simeprevir Preferred
TMC 435350 Narrower
TMC 435 Narrower
Olysio Narrower
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