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Bosentan MeSH Descriptor Data 2023


MeSH Heading
Bosentan
Tree Number(s)
D02.065.884.135
D02.886.590.700.143
D03.383.742.060
Unique ID
D000077300
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077300
Scope Note
A sulfonamide and pyrimidine derivative that acts as a dual endothelin receptor antagonist used to manage PULMONARY HYPERTENSION and SYSTEMIC SCLEROSIS.
Entry Term(s)
4-t-Butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
Bosentan Anhydrous
Bosentan Monohydrate
Ro 47-0203
Ro-47-0203
Tracleer
Pharm Action
Antihypertensive Agents
Endothelin Receptor Antagonists
Registry Number
Q326023R30
Related Numbers
147536-97-8
XUL93R30K2
CAS Type 1 Name
Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)(2,2'-bipyrimidin)-4-yl)-
Public MeSH Note
2019; BOSENTAN was indexed under SULFONAMIDES 1995-2018; and under RECEPTORS, ENDOTHELIN/antagonists 1994
History Note
2019 (1994)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/02/27
Bosentan Preferred
Bosentan Monohydrate Narrower
Tracleer Narrower
Bosentan Anhydrous Narrower
Ro 47-0203 Narrower
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