MeSH Browser

MeSH Heading: Metolazone
Tree Number(s): D02.065.884.600; D02.886.590.700.600; D03.633.100.786.830.688
Unique ID: D008788
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008788
Scope Note: A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
Entry Term(s): Diulo; Microx; Mykrox; SR-720-22; Zaroxolyn
Pharm Action: Antihypertensive Agents
Diuretics
Sodium Chloride Symporter Inhibitors
Related Numbers: 17560-51-9
CAS Type 1 Name: 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-
Previous Indexing: Diuretics, Sulfamyl (1974); Quinazolines (1971-1974)
Public MeSH Note: 91; was see under DIURETICS, SULFAMYL 1975-90
History Note: 91(75); was see under DIURETICS, SULFAMYL 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Metolazone MeSH Descriptor Data 2025