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T-Lymphoma Invasion and Metastasis-inducing Protein 1 MeSH Descriptor Data 2023


MeSH Heading
T-Lymphoma Invasion and Metastasis-inducing Protein 1
Tree Number(s)
D12.644.360.325.300.850
D12.776.476.325.300.850
Unique ID
D000075684
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000075684
Scope Note
A Rho guanine nucleotide exchange factor that consists of two pleckstrin homology domains flanking central Ras-binding, Dbl-homology (DH) and PDZ domains. It stimulates GTP-GDP exchange of rho-like GTPases such as RAC1 PROTEIN; CDC42 PROTEIN; and RHOA PROTEIN, and functions to link extracellular signals to remodeling of the CYTOSKELETON for CELL ADHESION and CELL MOVEMENT.
Entry Term(s)
TIAM-1 Protein
TIAM1 Protein
Registry Number
0
Previous Indexing
Guanine Nucleotide Exchange Factors (2007-2017)
See Also
PDZ Domains
Pleckstrin Homology Domains
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/06/29
T-Lymphoma Invasion and Metastasis-inducing Protein 1 Preferred
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