- Concept UI
- M000631113
- Registry Numbers
- 0
- Scope Note
- A Rho guanine nucleotide exchange factor that consists of two pleckstrin homology domains flanking central Ras-binding, Dbl-homology (DH) and PDZ domains. It stimulates GTP-GDP exchange of rho-like GTPases such as RAC1 PROTEIN; CDC42 PROTEIN; and RHOA PROTEIN, and functions to link extracellular signals to remodeling of the CYTOSKELETON for CELL ADHESION and CELL MOVEMENT.
- Terms
-
T-Lymphoma Invasion and Metastasis-inducing Protein 1
Preferred Term
Term UI
T000923443
Date05/05/2017
LexicalTag
NON
ThesaurusID
NLM (2018)
-
TIAM1 Protein
Term UI
T000923444
Date05/05/2017
LexicalTag
ACX
ThesaurusID
NLM (2018)
-
TIAM-1 Protein
Term UI
T000923445
Date05/05/2017
LexicalTag
ACX
ThesaurusID
NLM (2018)