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Locked-In Syndrome MeSH Descriptor Data 2023


MeSH Heading
Locked-In Syndrome
Tree Number(s)
C10.597.622.760.500
C10.668.416
C23.888.592.636.786.500
Unique ID
D000080422
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000080422
Scope Note
Acquired neuromuscular disorder characterized by complete paralysis of voluntary muscles and lower CRANIAL NERVES except for limited voluntary eye movements. It is due to various cerebrospinal disconnections at or near the PONS and the POSTERIOR CRANIAL FOSSA, typically secondary to pontine hemorrhage or infarct. Because cognitive function is intact it is sometimes referred to as a pseudocoma state.
Entry Term(s)
Cerebromedullospinal Disconnection
Ventral Pontine Syndrome
Public MeSH Note
2020; see QUADRIPLEGIA 1981-2019
History Note
2020(1981)
Date Established
2020/01/01
Date of Entry
2019/07/08
Revision Date
2019/04/29
Locked-In Syndrome Preferred
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