MeSH Browser

MeSH Heading: Locked-In Syndrome
Tree Number(s): C10.597.622.760.500; C10.668.416; C23.888.592.636.786.500
Unique ID: D000080422
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000080422
Scope Note: Acquired neuromuscular disorder characterized by complete paralysis of voluntary muscles and lower CRANIAL NERVES except for limited voluntary eye movements. It is due to various cerebrospinal disconnections at or near the PONS and the POSTERIOR CRANIAL FOSSA, typically secondary to pontine hemorrhage or infarct. Because cognitive function is intact it is sometimes referred to as a pseudocoma state.
Entry Term(s): Cerebromedullospinal Disconnection; Ventral Pontine Syndrome
Public MeSH Note: 2020; see QUADRIPLEGIA 1981-2019
History Note: 2020(1981)
Date Established: 2020/01/01
Date of Entry: 2019/07/08
Revision Date: 2019/04/29

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0018312
Scope Note: Acquired neuromuscular disorder characterized by complete paralysis of voluntary muscles and lower CRANIAL NERVES except for limited voluntary eye movements. It is due to various cerebrospinal disconnections at or near the PONS and the POSTERIOR CRANIAL FOSSA, typically secondary to pontine hemorrhage or infarct. Because cognitive function is intact it is sometimes referred to as a pseudocoma state.
Terms: Locked-In Syndrome Preferred Term
Term UI T034815
Date02/24/1981
LexicalTag NON
ThesaurusID UNK (19XX); Ventral Pontine Syndrome
Term UI T000952151
Date02/25/2019
LexicalTag NON
ThesaurusID NLM (2020); Cerebromedullospinal Disconnection
Term UI T000952137
Date02/25/2019
LexicalTag NON
ThesaurusID NLM (2020)

Locked-In Syndrome MeSH Descriptor Data 2025