NLM Logo

Cytochrome P-450 CYP2J2 MeSH Descriptor Data 2023


MeSH Heading
Cytochrome P-450 CYP2J2
Tree Number(s)
D08.244.453.003
D08.811.682.690.708.170.005
D10.251.355.128
D12.776.422.220.453.005
Unique ID
D000090762
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000090762
Scope Note
A cytochrome P450 enzyme involved in oxidizing POLYUNSATURATED FATTY ACIDS (PUFA) to PUFA epoxides which function as potent lipid mediators. This enzyme, encoded by CYP2J2 gene, metabolizes ARACHIDONIC ACID to epoxyeicosatrienoic acids (EETs) which produce biological effects including VASODILATION.
Entry Term(s)
Arachidonate Epoxygenase
Arachidonic Acid Epoxygenase
CYP2J2
Cytochrome P-450 Arachidonate Oxygenase
Cytochrome P-450 Epoxygenase
NADPH-Dependent Arachidonic Acid Epoxygenase
Registry Number
EC 1.14.14.1
Public MeSH Note
2022; ARACHIDONATE EPOXYGENASE was indexed under CYTOCHROME P-450 ENZYME SYSTEM 1987-2021, and under OXYGENASES 1985-2008
History Note
2022 (1985)
Date Established
2022/01/01
Date of Entry
2021/07/09
Revision Date
2021/06/28
Cytochrome P-450 CYP2J2 Preferred
Arachidonate Epoxygenase Broader
page delivered in 0.177s