MeSH Browser

MeSH Heading: Emetine
Tree Number(s): D03.132.316; D03.633.100.531.321
Unique ID: D004640
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004640
Scope Note: The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.
Entry Term(s): Emetine Dihydrochloride; Emetine Hydrochloride; Ipecine; Methylcephaeline
Pharm Action: Amebicides
Antinematodal Agents
Cathartics
Emetics
Protein Synthesis Inhibitors
Related Numbers: 316-42-7; 483-18-1; U52OG12P96
CAS Type 1 Name: Emetan, 6',7',10,11-tetramethoxy-
NLM Classification #: QV 255
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/12/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0007281
Related Numbers: 316-42-7; 483-18-1; U52OG12P96
Scope Note: The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.
Terms: Emetine Preferred Term
Term UI T014163
Date01/01/1999
LexicalTag NON
ThesaurusID; Ipecine
Term UI T014164
Date03/04/1977
LexicalTag NON
ThesaurusID UNK (19XX); Methylcephaeline
Term UI T014165
Date03/04/1977
LexicalTag NON
ThesaurusID UNK (19XX)

Emetine MeSH Descriptor Data 2025