MeSH Browser

MeSH Heading: Sjogren-Larsson Syndrome
Tree Number(s): C16.131.831.512.723; C16.320.565.398.641.723; C16.320.850.820; C16.614.492.723; C17.800.428.333.723; C17.800.804.512.723; C17.800.827.820; C18.452.584.563.641.723; C18.452.648.398.641.723
Unique ID: D016111
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016111
Annotation: do not confuse with SJOGREN'S SYNDROME; in titles & translations use diacritic: Sjögren-Larsson
Scope Note: An autosomal recessive neurocutaneous disorder characterized by severe ichthyosis MENTAL RETARDATION; SPASTIC PARAPLEGIA; and congenital ICHTHYOSIS. It is caused by mutation of gene encoding microsomal fatty ALDEHYDE DEHYDROGENASE leading to defect in fatty alcohol metabolism.
Entry Term(s): Congenital Icthyosis Mental Retardation Spasticity Syndrome; FALDH Deficiency; Fatty Alcohol:NAD+ Oxidoreductase Deficiency; Fatty Aldehyde Dehydrogenase Deficiency; Fatty Aldehyde Dehydrogenase Deficiency Disease; Ichthyosis Oligophrenia Syndrome; Ichthyosis, Spastic Neurologic Disorder, and Oligophrenia; Sjögren-Larsson Syndrome
Previous Indexing: Ichthyosis (1966-1990)
Public MeSH Note: 1991; see ICHTHYOSIS 1984-1990
History Note: 1991; use ICHTHYOSIS 1984-1990
Date Established: 1991/01/01
Date of Entry: 1990/06/06
Revision Date: 2021/07/01

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Sjogren-Larsson Syndrome MeSH Descriptor Data 2023