MeSH Browser

MeSH Heading: Porphyrias, Hepatic
Tree Number(s): C06.552.830; C16.320.850.742; C17.800.827.742; C18.452.811.400
Unique ID: D017094
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017094
Annotation: do not confuse with PORPHYRIA, ERYTHROHEPATIC
Scope Note: A group of metabolic diseases due to deficiency of one of a number of LIVER enzymes in the biosynthetic pathway of HEME. They are characterized by the accumulation and increased excretion of PORPHYRINS or its precursors. Clinical features include neurological symptoms (PORPHYRIA, ACUTE INTERMITTENT), cutaneous lesions due to photosensitivity (PORPHYRIA CUTANEA TARDA), or both (HEREDITARY COPROPORPHYRIA). Hepatic porphyrias can be hereditary or acquired as a result of toxicity to the hepatic tissues.
Entry Term(s): Hepatic Porphyria; Porphyria, Hepatic
Previous Indexing: Porphyria (1966-1992)
Public MeSH Note: 2005; see PORPHYRIA, HEPATIC 1993-2004
History Note: 2005 (1993)
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2015/06/05

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0025973
Scope Note: A group of metabolic diseases due to deficiency of one of a number of LIVER enzymes in the biosynthetic pathway of HEME. They are characterized by the accumulation and increased excretion of PORPHYRINS or its precursors. Clinical features include neurological symptoms (PORPHYRIA, ACUTE INTERMITTENT), cutaneous lesions due to photosensitivity (PORPHYRIA CUTANEA TARDA), or both (HEREDITARY COPROPORPHYRIA). Hepatic porphyrias can be hereditary or acquired as a result of toxicity to the hepatic tissues.
Terms: Porphyrias, Hepatic Preferred Term
Term UI T551611
Date09/25/2003
LexicalTag NON
ThesaurusID NLM (2005); Hepatic Porphyria
Term UI T051035
Date10/23/1991
LexicalTag NON
ThesaurusID NLM (1993); Porphyria, Hepatic
Term UI T051036
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1993)

Porphyrias, Hepatic MeSH Descriptor Data 2025