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MERRF Syndrome MeSH Descriptor Data 2021


MeSH Heading
MERRF Syndrome
Tree Number(s)
C05.651.460.620.530
C10.228.140.163.100.545
C10.228.140.490.375.130.650.700
C10.228.140.490.493.063.650.700
C10.668.491.500.500.550
C16.320.565.189.545
C18.452.132.100.545
C18.452.648.189.545
C18.452.660.560.620.530
Unique ID
D017243
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017243
Scope Note
A mitochondrial encephalomyopathy characterized clinically by a mixed seizure disorder, myoclonus, progressive ataxia, spasticity, and a mild myopathy. Dysarthria, optic atrophy, growth retardation, deafness, and dementia may also occur. This condition tends to present in childhood and to be transmitted via maternal lineage. Muscle biopsies reveal ragged-red fibers and respiratory chain enzymatic defects. (From Adams et al., Principles of Neurology, 6th ed, p986)
Entry Term(s)
Fukuhara Disease
Fukuhara Syndrome
MERRF
Myoclonic Epilepsy Associated with Ragged-Red Fibers
Myoclonic Epilepsy and Ragged Red Fibers
Myoclonic Epilepsy with Ragged Red Fibers
Myoclonic Epilepsy with Ragged-Red Fibers
Myoclonus with Epilepsy with Ragged Red Fibers
Myoencephalopathy Ragged-Red Fiber Disease
Previous Indexing
Epilepsy, Myoclonic (1980-1992)
Mitochondria, Muscle (1980-1992)
Public MeSH Note
1993
History Note
1993
Date Established
1993/01/01
Date of Entry
1992/05/22
Revision Date
2017/02/24
MERRF Syndrome Preferred
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