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Complement C3-C5 Convertases MeSH Descriptor Data 2022


MeSH Heading
Complement C3-C5 Convertases
Tree Number(s)
D12.776.124.486.274.045.387
Unique ID
D050577
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050577
Scope Note
Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B, or cleave COMPLEMENT C5 into COMPLEMENT C5A and COMPLEMENT C5B. These include the different forms of C3/C5 convertases in the classical and the alternative pathways of COMPLEMENT ACTIVATION. Both cleavages take place at the C-terminal of an ARGININE residue.
Entry Term(s)
C 3 Convertase
C3 Activator
C3 Convertase
C3-C5 Convertase
C5 Cleaving Enzyme
C5 Convertase
Complement 3 Convertase
Complement 5 Convertase
Complement C3 Convertases
Complement C5 Convertases
Pharm Action
Immunologic Factors
Registry Number
EC 3.4.21.-
Previous Indexing
Complement C3 (1976-2005)
Complement C5 (1976-2005)
Public MeSH Note
2006; for COMPLEMENT 3 CONVERTASE see COMPLEMENT 3 CONVERTASE 1991-2005, see COMPLEMENT ACTIVATING ENZYMES 1978-1990
History Note
2006 (1978)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2006/07/05
Complement C3-C5 Convertases Preferred
Complement C3 Convertases Narrower
Complement C5 Convertases Narrower
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