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Complement C3 Convertase, Alternative Pathway MeSH Descriptor Data 2023


MeSH Heading
Complement C3 Convertase, Alternative Pathway
Tree Number(s)
D12.776.124.486.274.045.387.500.374
Unique ID
D051561
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051561
Scope Note
A serine protease that is the complex of COMPLEMENT C3B and COMPLEMENT FACTOR BB. It cleaves multiple COMPLEMENT C3 into COMPLEMENT C3A (anaphylatoxin) and COMPLEMENT C3B in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY.
Entry Term(s)
Alternative Pathway C3 Convertase
C3 Convertase (C3bBb)
C3 Convertase, Alternative Pathway
CVFBb
Complement 3 Convertase, Alternative Pathway
Complement 3b-Associated Factor B-fragment Bb
Complement C3 Convertase, CVFBb
Pharm Action
Immunologic Factors
Registry Number
EC 3.4.21.47
Related Numbers
EC 3.4.21.47
Previous Indexing
Complement C3 (1976-2005)
Esterases (1976-2005)
Public MeSH Note
2006; was indexed under COMPLEMENT 3B 1989-2005; for CVFBB see COMPLEMENT FACTOR B 1985-2005
History Note
2006 (1989); for CVFBB use COMPLEMENT FACTOR B 1985-2005
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2006/07/05
Complement C3 Convertase, Alternative Pathway Preferred
Complement C3 Convertase, CVFBb Related
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