Microphthalmia-Associated Transcription Factor MeSH Descriptor Data 2025

MeSH Heading: Microphthalmia-Associated Transcription Factor
Tree Number(s): D12.776.260.103.500.500; D12.776.260.108.092.500; D12.776.930.125.500.500; D12.776.930.127.092.500
Unique ID: D051739
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051739
Scope Note: A basic helix-loop-helix leucine zipper transcription factor that regulates the CELL DIFFERENTIATION and development of a variety of cell types including MELANOCYTES; OSTEOCLASTS; and RETINAL PIGMENT EPITHELIUM. Mutations in MITF protein have been associated with OSTEOPETROSIS and WAARDENBURG SYNDROME.
Entry Term(s): MITF Protein; MITF Transcription Factor; Transcription Factor Microphthalmia
Public MeSH Note: 2006; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1993-2005
History Note: 2006(1993)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2012/07/03

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - DNA-Binding Proteins [D12.776.260]
    - Basic Helix-Loop-Helix Transcription Factors [D12.776.260.103]
      - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors [D12.776.260.103.500]
        
        Microphthalmia-Associated Transcription Factor [D12.776.260.103.500.500]
        
        N-Myc Proto-Oncogene Protein [D12.776.260.103.500.625]
        
        Sterol Regulatory Element Binding Proteins [D12.776.260.103.500.750]
        
        Transcription Factor 3 [D12.776.260.103.500.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - DNA-Binding Proteins [D12.776.260]
    - Basic-Leucine Zipper Transcription Factors [D12.776.260.108]
      - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors [D12.776.260.108.092]
        
        Microphthalmia-Associated Transcription Factor [D12.776.260.108.092.500]
        
        N-Myc Proto-Oncogene Protein [D12.776.260.108.092.625]
        
        Sterol Regulatory Element Binding Proteins [D12.776.260.108.092.750]
        
        Transcription Factor 3 [D12.776.260.108.092.875]
        
        Transcription Factor 4 [D12.776.260.108.092.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Transcription Factors [D12.776.930]
    - Basic Helix-Loop-Helix Transcription Factors [D12.776.930.125]
      - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors [D12.776.930.125.500]
        
        Microphthalmia-Associated Transcription Factor [D12.776.930.125.500.500]
        
        N-Myc Proto-Oncogene Protein [D12.776.930.125.500.563]
        
        Nuclear Receptor Coactivator 1 [D12.776.930.125.500.625]
        
        Sterol Regulatory Element Binding Proteins [D12.776.930.125.500.750]
        
        Transcription Factor 3 [D12.776.930.125.500.875]
        
        Transcription Factor 4 [D12.776.930.125.500.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Transcription Factors [D12.776.930]
    - Basic-Leucine Zipper Transcription Factors [D12.776.930.127]
      - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors [D12.776.930.127.092]
        
        Microphthalmia-Associated Transcription Factor [D12.776.930.127.092.500]
        
        N-Myc Proto-Oncogene Protein [D12.776.930.127.092.625]
        
        Sterol Regulatory Element Binding Proteins [D12.776.930.127.092.750]
        
        Transcription Factor 3 [D12.776.930.127.092.875]

Microphthalmia-Associated Transcription Factor Preferred

page delivered in 0.162s