MeSH Browser

MeSH Heading: Sterol Regulatory Element Binding Protein 1
Tree Number(s): D12.776.260.103.500.750.500; D12.776.260.108.092.750.500; D12.776.930.125.500.750.500; D12.776.930.127.092.750.500
Unique ID: D051780
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051780
Scope Note: A sterol regulatory element binding protein that regulates expression of GENES involved in FATTY ACIDS metabolism and LIPOGENESIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING.
Entry Term(s): Adipocyte Determination And Differentiation Factor 1; SRE-1 Binding Protein; SREBP-1a; SREBP-1c; SREBP1 Protein; Sterol Regulatory Element Binding Protein 1a; Sterol Regulatory Element Binding Protein 1c; Sterol Regulatory Element-Binding Protein 1; Transcription Factor ADD1
Registry Numbers: 0
Public MeSH Note: 2006; STEROL REGULATORY ELEMENT BINDING PROTEIN 1 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1993-2005, & under CCAAT-ENHANCER-BINDING PROTEINS 2001-2005, & under NUCLEAR PROTEINS 1999-2000
History Note: 2006(1993)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2009/07/17

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0218287
Registry Numbers: 0
Scope Note: A sterol regulatory element binding protein that regulates expression of GENES involved in FATTY ACIDS metabolism and LIPOGENESIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING.
Terms: Sterol Regulatory Element Binding Protein 1 Preferred Term
Term UI T632940
Date03/10/2005
LexicalTag NON
ThesaurusID NLM (2006); SRE-1 Binding Protein
Term UI T248292
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); SREBP1 Protein
Term UI T632941
Date03/10/2005
LexicalTag ABX
ThesaurusID NLM (2006); Sterol Regulatory Element-Binding Protein 1
Term UI T248290
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006)

Concept UI: M0350711
Registry Numbers: 0
Scope Note: SREBP1-C is an isoform of sterol regulatory element binding protein 1 that is a weak activator of GENETIC TRANSCRIPTION. It is the predominant form in LIVER and ADIPOCYTES, and it mediates INSULIN induced FATTY ACIDS synthesis.
Terms: Sterol Regulatory Element Binding Protein 1c Preferred Term
Term UI T632957
Date03/10/2005
LexicalTag NON
ThesaurusID NLM (2006); Adipocyte Determination And Differentiation Factor 1
Term UI T632942
Date03/10/2005
LexicalTag NON
ThesaurusID NLM (2006); SREBP-1c
Term UI T400823
Date11/26/1999
LexicalTag ABX
ThesaurusID NLM (2006); Transcription Factor ADD1
Term UI T248291
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2006)

Sterol Regulatory Element Binding Protein 1 MeSH Descriptor Data 2024