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alpha-Synuclein
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
alpha-Synuclein
Tree Number(s)
D12.776.631.860.500
D12.776.705.500
Unique ID
D051844
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051844
Scope Note
A synuclein that is a major component of
LEWY BODIES
and plays a role in
SYNUCLEINOPATHIES
, neurodegeneration and neuroprotection.
Entry Term(s)
Non-AB Component of AD Amyloid Protein
Registry Numbers
0
See Also
Synucleinopathies
Public MeSH Note
2006; ALPHA-SYNUCLEIN was indexed under NERVE TISSUE PROTEINS 1988-2005
History Note
2006(1988)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2022/07/12
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
agonists (AG)
analysis (AN)
antagonists & inhibitors (AI)
biosynthesis (BI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
deficiency (DF)
drug effects (DE)
economics (EC)
genetics (GE)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
physiology (PH)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
ultrastructure (UL)
urine (UR)
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Nerve Tissue Proteins [D12.776.631]
Synucleins [D12.776.631.860]
alpha-Synuclein [D12.776.631.860.500]
beta-Synuclein [D12.776.631.860.625]
gamma-Synuclein [D12.776.631.860.750]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Parkinson Disease Associated Proteins [D12.776.705]
alpha-Synuclein [D12.776.705.500]
High-Temperature Requirement A Serine Peptidase 2 [D12.776.705.625]
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 [D12.776.705.750]
Protein Deglycase DJ-1 [D12.776.705.875]
Ubiquitin Thiolesterase [D12.776.705.937]
Expand All
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alpha-Synuclein
Preferred
Concept UI
M0159750
Registry Numbers
0
Scope Note
A synuclein that is a major component of
LEWY BODIES
and plays a role in
SYNUCLEINOPATHIES
, neurodegeneration and neuroprotection.
Terms
alpha-Synuclein
Preferred Term
Term UI
T189755
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2006)
Non-AB Component of AD Amyloid Protein
Term UI
T633350
Date
03/15/2005
LexicalTag
NON
ThesaurusID
NLM (2006)
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