MeSH Browser

MeSH Heading: Protein Tyrosine Phosphatase, Non-Receptor Type 1
Tree Number(s): D08.811.277.352.650.775.300.100; D12.776.476.564.300.100
Unique ID: D054562
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054562
Scope Note: A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
Entry Term(s): PTPase 1B; PTPase HA2; Protein Tyrosine Phosphatase 1B; Protein-Tyrosine Phosphatase HA2
Previous Indexing: Protein Tyrosine Phosphatases (1991-2007)
Public MeSH Note: 2008; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1 was indexed under PROTEIN TYROSINE PHOSPHATASES 2000-2007, and under MEMBRANE PROTEINS & PROTEIN TYROSINE PHOSPHATASES 1999-2000; for PTPase 1B see PROTEIN-TYROSINE-PHOSPHATASE 1991-2007
History Note: 2008
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0331760
Scope Note: A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
Terms: Protein Tyrosine Phosphatase, Non-Receptor Type 1 Preferred Term
Term UI T690162
Date01/26/2007
LexicalTag NON
ThesaurusID NLM (2008); PTPase HA2
Term UI T276546
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2008); Protein-Tyrosine Phosphatase HA2
Term UI T276547
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2008); Protein Tyrosine Phosphatase 1B
Term UI T411497
Date04/08/2000
LexicalTag NON
ThesaurusID NLM (2008); PTPase 1B
Term UI T050833
Date04/03/1991
LexicalTag NON
ThesaurusID NLM (1992)

Protein Tyrosine Phosphatase, Non-Receptor Type 1 MeSH Descriptor Data 2025