MeSH Browser

MeSH Heading: Autophagy
Tree Number(s): G04.011
Unique ID: D001343
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D001343
Annotation: general or unspecified; note specifics; do not confuse with AUTOPHAGIC CELL DEATH, a form of regulated cell death
Scope Note: The segregation and degradation of various cytoplasmic constituents via engulfment by MULTIVESICULAR BODIES; VACUOLES; or AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.
Entry Term(s): Autophagocytosis; Autophagy, Cellular; ER-Phagy; Lipophagy; Nucleophagy; Reticulophagy; Ribophagy
NLM Classification #: QU 375
Previous Indexing: Autolysis (1968-1978); Lysosomes (1966-1978); Phagocytosis (1966-1978)
Public MeSH Note: 2006; see AUTOPHAGOCYTOSIS 1991-2005, PHAGOCYTOSIS 1979-1990
History Note: 2006(1979)
Date Established: 1991/01/01
Date of Entry: 1978/03/20
Revision Date: 2019/07/05

Autophagy MeSH Descriptor Data 2024