MeSH Browser

MeSH Heading: Glycogen Synthase Kinase 3 beta
Tree Number(s): D05.500.117.875.500; D08.811.913.696.620.682.700.429.500.500; D08.811.913.696.620.682.700.646.625.500; D12.776.476.081.875.500; D12.776.476.563.429.500.500; D12.776.476.563.646.625.500
Unique ID: D000071679
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071679
Scope Note: A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved in PROTEIN BIOSYNTHESIS and regulates cell growth and proliferation as a component of the WNT SIGNALING PATHWAY and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with PARKINSON DISEASE; ALZHEIMER DISEASE; and BIPOLAR DISORDER.
Entry Term(s): GSK-3beta; GSK3B Protein; GSK3beta
Public MeSH Note: 2017; GLYCOGEN SYNTHASE KINASE 3 BETA was indexed under GLYCOGEN SYNTHASE KINASE 3 2002-2016
History Note: 2017 (2002)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0143052
Scope Note: A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved in PROTEIN BIOSYNTHESIS and regulates cell growth and proliferation as a component of the WNT SIGNALING PATHWAY and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with PARKINSON DISEASE; ALZHEIMER DISEASE; and BIPOLAR DISORDER.
Terms: Glycogen Synthase Kinase 3 beta Preferred Term
Term UI T000896342
Date03/02/2016
LexicalTag NON
ThesaurusID NLM (2002); GSK3B Protein
Term UI T000896343
Date03/02/2016
LexicalTag ABX
ThesaurusID NLM (2017); GSK-3beta
Term UI T173057
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2003); GSK3beta
Term UI T748816
Date04/06/2009
LexicalTag ABX
ThesaurusID NLM (2009)

Glycogen Synthase Kinase 3 beta MeSH Descriptor Data 2025