- Concept UI
- M000747331
- Registry Numbers
- EC 1.5.1.25
- Related Numbers
- 147681-64-9
- Scope Note
- A subclass of crystallins expressed highly in lens of diurnal Australian MARSUPIALS and in neural tissue, muscle, and kidney in humans. It is not a structural protein accounting for the transparency of the human lens unlike other crystallins but instead plays a role in thyroid hormone bioavailability. It is also a cerebral ketimine reductase which reduces cyclic imines (e.g., DELTA(1)-PIPERIDINE-2-CARBOXYLIC ACID; CYSTATHIONINE KETIMINE and LANTHIONINE KETIMINE) in mammalian brain. Mutations in mu-crystallins are associated with an autosomal dominant NONSYNDROMIC DEAFNESS.
- Terms
-
mu-Crystallins
Preferred Term
Term UI
T001105132
Date04/23/2021
LexicalTag
NON
ThesaurusID
NLM (2022)
-
Crystallin mu
Term UI
T001107385
Date06/02/2021
LexicalTag
NON
ThesaurusID
NLM (2022)
-
Ketimine Reductase mu-Crystallin
Term UI
T001107386
Date06/02/2021
LexicalTag
NON
ThesaurusID
NLM (2022)
-
CRYM Protein
Term UI
T001107387
Date06/02/2021
LexicalTag
ABX
ThesaurusID
NLM (2022)
-
THBP Protein
Term UI
T001107406
Date06/02/2021
LexicalTag
ABX
ThesaurusID
NLM (2022)
-
NADP-Regulated Thyroid Hormone Binding Protein
Term UI
T001107405
Date06/02/2021
LexicalTag
NON
ThesaurusID
NLM (2022)