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Pyrroline Carboxylate Reductases MeSH Descriptor Data 2026
A group of enzymes that catalyze the reduction of 1-pyrroline carboxylate to proline in the presence of NAD(P)H. Includes both the 2-oxidoreductase (EC 1.5.1.1) and the 5-oxidoreductase (EC 1.5.1.2). The former also reduces 1-piperidine-2-carboxylate to pipecolate and the latter also reduces 1-pyrroline-3-hydroxy-5-carboxylate to hydroxyproline.
Registry Numbers
EC 1.5.1.-
Previous Indexing
Amine Oxidoreductases (1975-1976)
Oxidoreductases (1966-1974)
Public MeSH Note
91; was see under AMINE OXIDOREDUCTASES 1977-90
History Note
91(77); was see under AMINE OXIDOREDUCTASES 1977-90
A group of enzymes that catalyze the reduction of 1-pyrroline carboxylate to proline in the presence of NAD(P)H. Includes both the 2-oxidoreductase (EC 1.5.1.1) and the 5-oxidoreductase (EC 1.5.1.2). The former also reduces 1-piperidine-2-carboxylate to pipecolate and the latter also reduces 1-pyrroline-3-hydroxy-5-carboxylate to hydroxyproline.