Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Methylenetetrahydrofolate Reductase (NADPH2) MeSH Descriptor Data 2026


MeSH Heading
Methylenetetrahydrofolate Reductase (NADPH2)
Tree Number(s)
D08.811.682.662.290
D12.776.331.775
Unique ID
D042965
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D042965
Scope Note
A flavoprotein amine oxidoreductase that catalyzes the reversible conversion of 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. This enzyme was formerly classified as EC 1.1.1.171.
Entry Term(s)
5,10-Methylenetetrahydrofolate Reductase (NADPH)
Methylene Tetrahydrofolate Reductase
Methylene-THF Reductase (NADPH)
Methylenetetrahydrofolate Reductase
Methylenetetrahydrofolate Reductase (NADPH)
Registry Numbers
EC 1.5.1.20
Previous Indexing
Amine Oxidoreductases (1986-2003)
Public MeSH Note
2004; METHYLENE-THF-REDUCTASE (NADPH) was indexed under AMINE OXIDOREDUCTASES 1986-2003
History Note
2004; use METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2) (NM) 1986-2003
Date Introduced
2004/01/01
Last Updated
2010/06/25
Methylenetetrahydrofolate Reductase (NADPH2) Preferred
page delivered in 0.143s