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Saccharopine Dehydrogenases MeSH Descriptor Data 2025


MeSH Heading
Saccharopine Dehydrogenases
Tree Number(s)
D08.811.682.662.750
Unique ID
D012443
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D012443
Annotation
/defic: consider also HYPERLYSINEMIAS
Scope Note
Amine oxidoreductases that use either NAD+ (EC 1.5.1.7) or NADP+ (EC 1.5.1.8) as an acceptor to form L-LYSINE or NAD+ (EC 1.5.1.9) or NADP+ (EC 1.5.1.10) as an acceptor to form L-GLUTAMATE. Deficiency of this enzyme causes HYPERLYSINEMIAS.
Entry Term(s)
Lysine-2-Oxoglutarate Reductase
Lysine-Ketoglutarate Reductase
Saccharopine Dehydrogenase
Saccharopine Dehydrogenase (NAD+, L-Glutamate Forming)
Saccharopine Dehydrogenase (NAD+, L-Lysine Forming)
Saccharopine Dehydrogenase (NADP+, L-Glutamate Forming)
Saccharopine Dehydrogenase (NADP+, L-Lysine Forming)
Registry Numbers
EC 1.5.1.-
EC 1.5.1.7
EC 1.5.1.8
EC 1.5.1.9
EC 1.5.1.10
Related Numbers
EC 1.5.1.10
EC 1.5.1.7
EC 1.5.1.8
EC 1.5.1.9
Previous Indexing
Ketoglutaric Acids (1972-1974)
Lysine (1970-1974)
Oxidoreductases (1970-1974)
See Also
Hyperlysinemias
Public MeSH Note
91; was see under AMINE OXIDOREDUCTASES 1975-90
History Note
91(75); was see under AMINE OXIDOREDUCTASES 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/19
Revision Date
2021/06/30
Saccharopine Dehydrogenases Preferred
Saccharopine Dehydrogenase (NAD+, L-Lysine Forming) Narrower
Saccharopine Dehydrogenase (NADP+, L-Lysine Forming) Narrower
Saccharopine Dehydrogenase (NAD+, L-Glutamate Forming) Narrower
Saccharopine Dehydrogenase (NADP+, L-Glutamate Forming) Narrower
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