MeSH Browser

MeSH Heading: Sodium-Iodide Symporters
Tree Number(s): D12.776.157.530.450.625.531; D12.776.543.585.450.625.594
Unique ID: D000099209
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000099209
Scope Note: Proteins that cotransport sodium ions and iodide ions across cellular membranes. They function in the biosynthesis of TRIIODOTHYRONINE and THYROXINE.
Entry Term(s): NIS Protein; Na(+),I(-)-Cotransporter; Sodium Iodide Symporter; Sodium-Iodide Cotransporter; Sodium-Iodide Symporter; Thyroid Iodide Transporter
Registry Numbers: 4XE5NDT4K1
Public MeSH Note: 2026; SODIUM-IODIDE SYMPORTERS was indexed under SYMPORTERS 2001-2025, and under CARRIER PROTEINS and MEMBRANE PROTEINS 1991-2001
History Note: 2026 (1991)
Date Introduced: 2026/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Pumps [D12.776.157.530.450]
        
        Symporters [D12.776.157.530.450.625]
        
        Dopamine Plasma Membrane Transport Proteins [D12.776.157.530.450.625.124]
        
        GABA Plasma Membrane Transport Proteins [D12.776.157.530.450.625.139]
        
        Glutamate Plasma Membrane Transport Proteins [D12.776.157.530.450.625.147]
        
        Glycine Plasma Membrane Transport Proteins [D12.776.157.530.450.625.155]
        
        Monocarboxylate Transport Protein 1 [D12.776.157.530.450.625.171]
        
        Norepinephrine Plasma Membrane Transport Proteins [D12.776.157.530.450.625.186]
        
        Peptide Transporter 1 [D12.776.157.530.450.625.202]
        
        Proton-Coupled Folate Transporter [D12.776.157.530.450.625.217]
        
        Proton-Phosphate Symporters [D12.776.157.530.450.625.249]
        
        Serotonin Plasma Membrane Transport Proteins [D12.776.157.530.450.625.311]
        
        Sodium Chloride Symporters [D12.776.157.530.450.625.374]
        
        Sodium Sulfate Cotransporter [D12.776.157.530.450.625.390]
        
        Sodium-Coupled Vitamin C Transporters [D12.776.157.530.450.625.405]
        
        Sodium-Glucose Transport Proteins [D12.776.157.530.450.625.437]
        
        Sodium-Bicarbonate Symporters [D12.776.157.530.450.625.500]
        
        Sodium-Iodide Symporters [D12.776.157.530.450.625.531]
        
        Sodium-Phosphate Cotransporter Proteins [D12.776.157.530.450.625.625]
        
        Solute Carrier Family 12 [D12.776.157.530.450.625.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Pumps [D12.776.543.585.450]
        
        Symporters [D12.776.543.585.450.625]
        
        Dopamine Plasma Membrane Transport Proteins [D12.776.543.585.450.625.124]
        
        GABA Plasma Membrane Transport Proteins [D12.776.543.585.450.625.139]
        
        Glutamate Plasma Membrane Transport Proteins [D12.776.543.585.450.625.147]
        
        Glycine Plasma Membrane Transport Proteins [D12.776.543.585.450.625.155]
        
        K Cl- Cotransporters [D12.776.543.585.450.625.171]
        
        Monocarboxylate Transport Protein 1 [D12.776.543.585.450.625.179]
        
        Norepinephrine Plasma Membrane Transport Proteins [D12.776.543.585.450.625.186]
        
        Peptide Transporter 1 [D12.776.543.585.450.625.202]
        
        Proton-Coupled Folate Transporter [D12.776.543.585.450.625.217]
        
        Proton-Phosphate Symporters [D12.776.543.585.450.625.249]
        
        Serotonin Plasma Membrane Transport Proteins [D12.776.543.585.450.625.374]
        
        Sodium Sulfate Cotransporter [D12.776.543.585.450.625.437]
        
        Sodium-Bicarbonate Symporters [D12.776.543.585.450.625.500]
        
        Sodium-Coupled Vitamin C Transporters [D12.776.543.585.450.625.531]
        
        Sodium-Glucose Transport Proteins [D12.776.543.585.450.625.562]
        
        Sodium-Iodide Symporters [D12.776.543.585.450.625.594]
        
        Sodium-Phosphate Cotransporter Proteins [D12.776.543.585.450.625.625]
        
        Sodium-Potassium-Chloride Symporters [D12.776.543.585.450.625.750]
        
        Solute Carrier Family 12 [D12.776.543.585.450.625.875]

Sodium-Iodide Symporters Preferred

Concept UI: M000768956
Registry Numbers: 4XE5NDT4K1
Scope Note: Proteins that cotransport sodium ions and iodide ions across cellular membranes. They function in the biosynthesis of TRIIODOTHYRONINE and THYROXINE.
Terms: Sodium-Iodide Symporters Preferred Term
Term UI T001148110
Date04/16/2025
LexicalTag NON
ThesaurusID NLM (2026); Na(+),I(-)-Cotransporter
Term UI T001148117
Date04/16/2025
LexicalTag NON
ThesaurusID NLM (2026); NIS Protein
Term UI T001148112
Date04/16/2025
LexicalTag NON
ThesaurusID NLM (2026); Sodium Iodide Symporter
Term UI T001148113
Date04/16/2025
LexicalTag NON
ThesaurusID NLM (2026); Sodium-Iodide Cotransporter
Term UI T001148114
Date04/16/2025
LexicalTag NON
ThesaurusID NLM (2026); Sodium-Iodide Symporter
Term UI T001148115
Date04/16/2025
LexicalTag NON
ThesaurusID NLM (2026); Thyroid Iodide Transporter
Term UI T001148116
Date04/16/2025
LexicalTag NON
ThesaurusID NLM (2026)

Sodium-Iodide Symporters MeSH Descriptor Data 2026