MeSH Browser

MeSH Heading: Benzopyrene Hydroxylase
Tree Number(s): D08.244.453.005.110; D08.811.682.690.708.170.010.110; D12.776.422.220.453.010.110
Unique ID: D001579
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D001579
Annotation: a cytochrome
Scope Note: A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. Also acts on certain anthracene derivatives. An aspect of EC 1.14.14.1.
Entry Term(s): Benzo(a)pyrene Hydroxylase; Benzo(a)pyrene Monooxygenase; Benzopyrene-3-Monooxygenase
Previous Indexing: Benzopyrenes (1968-1974); Hydroxylases (1968-1974)
Public MeSH Note: 91; was see under ARYL HYDROCARBON HYDROXYLASES 1977-90; was see under HYDROXYLASES 1975-76
History Note: 91(75); was see under ARYL HYDROCARBON HYDROXYLASES 1977-90; was see under HYDROXYLASES 1975-76
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0002368
Scope Note: A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. Also acts on certain anthracene derivatives. An aspect of EC 1.14.14.1.
Terms: Benzopyrene Hydroxylase Preferred Term
Term UI T004573
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Benzo(a)pyrene Hydroxylase
Term UI T004571
Date12/02/1981
LexicalTag NON
ThesaurusID UNK (19XX); Benzo(a)pyrene Monooxygenase
Term UI T004572
Date11/28/1986
LexicalTag NON
ThesaurusID UNK (19XX); Benzopyrene-3-Monooxygenase
Term UI T004574
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX)

Benzopyrene Hydroxylase MeSH Descriptor Data 2025