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Prion Diseases MeSH Descriptor Data 2023


MeSH Heading
Prion Diseases
Tree Number(s)
C01.207.800
C10.228.228.800
C10.574.843
Unique ID
D017096
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017096
Annotation
general or unspecified; prefer specifics
Scope Note
A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83)
Entry Version
PRION DIS
Entry Term(s)
Dementias, Transmissible
Encephalopathies, Spongiform, Transmissible
Human Transmissible Spongiform Encephalopathies, Inherited
Inherited Human Transmissible Spongiform Encephalopathies
Prion Disease
Prion Protein Diseases
Prion-Associated Disorders
Prion-Induced Disorder
Prion-Induced Disorders
Spongiform Encephalopathies, Transmissible
Transmissible Dementias
Transmissible Spongiform Encephalopathies
NLM Classification #
WL 301
Previous Indexing
Slow Virus Diseases (1966-1992)
Public MeSH Note
1993
History Note
1993
Date Established
1993/01/01
Date of Entry
1992/05/22
Revision Date
2019/06/17
Prion Diseases Preferred
Human Transmissible Spongiform Encephalopathies, Inherited Narrower
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