MeSH Browser

MeSH Heading: Prion Diseases
Tree Number(s): C01.207.800; C10.228.228.800; C10.574.843
Unique ID: D017096
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017096
Annotation: general or unspecified; prefer specifics
Scope Note: A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83)
Entry Version: PRION DIS
Entry Term(s): Dementias, Transmissible; Encephalopathies, Spongiform, Transmissible; Human Transmissible Spongiform Encephalopathies, Inherited; Inherited Human Transmissible Spongiform Encephalopathies; Prion Disease; Prion Protein Diseases; Prion-Associated Disorders; Prion-Induced Disorder; Prion-Induced Disorders; Spongiform Encephalopathies, Transmissible; Transmissible Dementias; Transmissible Spongiform Encephalopathies
NLM Classification #: WL 301
Previous Indexing: Slow Virus Diseases (1966-1992)
Public MeSH Note: 1993
History Note: 1993
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2019/06/17

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

transmission (TM)

urine (UR)

veterinary (VE)

virology (VI)

Infections [C01]
- Central Nervous System Infections [C01.207]

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Central Nervous System Infections [C10.228.228]

Nervous System Diseases [C10]
- Neurodegenerative Diseases [C10.574]

Prion Diseases Preferred

Concept UI: M0025975
Scope Note: A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83)
Terms: Prion Diseases Preferred Term
Term UI T051045
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1993); Dementias, Transmissible
Term UI T051043
Date10/01/1991
LexicalTag NON
ThesaurusID NLM (1993); Transmissible Dementias
Term UI T051044
Date10/01/1991
LexicalTag NON
ThesaurusID; Encephalopathies, Spongiform, Transmissible
Term UI T370036
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000); Prion Protein Diseases
Term UI T370037
Date11/08/1999
LexicalTag NON
ThesaurusID; Prion-Induced Disorder
Term UI T370038
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000); Transmissible Spongiform Encephalopathies
Term UI T370039
Date11/08/1999
LexicalTag NON
ThesaurusID; Prion Disease
Term UI T842325
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014); Prion-Associated Disorders
Term UI T842326
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014); Spongiform Encephalopathies, Transmissible
Term UI T051042
Date10/11/1991
LexicalTag NON
ThesaurusID NLM (1993); Prion-Induced Disorders
Term UI T842327
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014)

Human Transmissible Spongiform Encephalopathies, Inherited Narrower

Prion Diseases MeSH Descriptor Data 2025