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Integrin alpha4beta1 MeSH Descriptor Data 2023


MeSH Heading
Integrin alpha4beta1
Tree Number(s)
D12.776.395.550.200.625.347
D12.776.543.550.200.625.347
D12.776.543.750.705.408.530.500
D12.776.543.750.705.408.850.299
D12.776.543.750.705.877.347
D23.050.301.350.625.347
Unique ID
D039041
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D039041
Scope Note
Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.
Entry Term(s)
CD49d-CD29
Integrin Heterodimer alpha4beta1
Integrin alpha(4)beta(1)
VLA-4
Very Late Activation Antigen-4
Very Late Antigen-4
alpha4beta1 Integrin
Registry Number
0
Previous Indexing
Integrins (1991-2002)
Receptors, Lymphocyte Homing (1991-2002)
Public MeSH Note
2003; INTEGRIN ALPHA4BETA1 was indexed under INTEGRINS and RECEPTORS, LYMPHOCYTE HOMING 1991-2002
History Note
2003 (1991)
Date Established
2003/01/01
Date of Entry
2002/07/02
Revision Date
2017/05/24
Integrin alpha4beta1 Preferred
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