Matrix Metalloproteinase 13 MeSH Descriptor Data 2025

MeSH Heading: Matrix Metalloproteinase 13
Tree Number(s): D08.811.277.656.300.480.205.363; D08.811.277.656.300.480.525.700.550; D08.811.277.656.675.374.205.363; D08.811.277.656.675.374.525.700.550; D12.776.467.836.550
Unique ID: D053509
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053509
Scope Note: A secreted matrix metalloproteinase that plays a physiological role in the degradation of extracellular matrix found in skeletal tissues. It is synthesized as an inactive precursor that is activated by the proteolytic cleavage of its N-terminal propeptide.
Entry Term(s): Collagenase 3; Collagenase-3; MMP-13 Metalloproteinase; MMP13 Metalloproteinase; Matrix Metalloproteinase-13
Public MeSH Note: 2007; MATRIX METALLOPROTEINASE 13 was indexed under COLLAGENASES 1994-2006
History Note: 2007(1994)
Entry Combination: antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2021/05/21

Entry Combination: antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Metalloendopeptidases [D08.811.277.656.300.480]
        
        Collagenases [D08.811.277.656.300.480.205]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.300.480.205.351]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.300.480.205.352]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.300.480.205.358]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.300.480.205.360]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.300.480.205.363]
        
        Microbial Collagenase [D08.811.277.656.300.480.205.500]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Metalloendopeptidases [D08.811.277.656.300.480]
        
        Matrix Metalloproteinases [D08.811.277.656.300.480.525]
        
        Matrix Metalloproteinases, Secreted [D08.811.277.656.300.480.525.700]
        
        Bone Morphogenetic Protein 1 [D08.811.277.656.300.480.525.700.049]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.300.480.525.700.100]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.300.480.525.700.150]
        
        Matrix Metalloproteinase 3 [D08.811.277.656.300.480.525.700.200]
        
        Matrix Metalloproteinase 7 [D08.811.277.656.300.480.525.700.250]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.300.480.525.700.300]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.300.480.525.700.350]
        
        Matrix Metalloproteinase 10 [D08.811.277.656.300.480.525.700.400]
        
        Matrix Metalloproteinase 11 [D08.811.277.656.300.480.525.700.450]
        
        Matrix Metalloproteinase 12 [D08.811.277.656.300.480.525.700.500]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.300.480.525.700.550]
        
        Matrix Metalloproteinase 20 [D08.811.277.656.300.480.525.700.800]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Metalloproteases [D08.811.277.656.675]
        
        Metalloendopeptidases [D08.811.277.656.675.374]
        
        Collagenases [D08.811.277.656.675.374.205]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.675.374.205.351]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.675.374.205.352]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.675.374.205.358]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.675.374.205.360]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.675.374.205.363]
        
        Microbial Collagenase [D08.811.277.656.675.374.205.500]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Metalloproteases [D08.811.277.656.675]
        
        Metalloendopeptidases [D08.811.277.656.675.374]
        
        Matrix Metalloproteinases [D08.811.277.656.675.374.525]
        
        Matrix Metalloproteinases, Secreted [D08.811.277.656.675.374.525.700]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.675.374.525.700.100]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.675.374.525.700.150]
        
        Matrix Metalloproteinase 3 [D08.811.277.656.675.374.525.700.200]
        
        Matrix Metalloproteinase 7 [D08.811.277.656.675.374.525.700.250]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.675.374.525.700.300]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.675.374.525.700.350]
        
        Matrix Metalloproteinase 10 [D08.811.277.656.675.374.525.700.400]
        
        Matrix Metalloproteinase 11 [D08.811.277.656.675.374.525.700.450]
        
        Matrix Metalloproteinase 12 [D08.811.277.656.675.374.525.700.500]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.675.374.525.700.550]
        
        Matrix Metalloproteinase 20 [D08.811.277.656.675.374.525.700.800]
        
        Tolloid-Like Metalloproteinases [D08.811.277.656.675.374.525.700.900]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intercellular Signaling Peptides and Proteins [D12.776.467]
    - Matrix Metalloproteinases, Secreted [D12.776.467.836]

Matrix Metalloproteinase 13 Preferred

Concept UI: M0232202
Scope Note: A secreted matrix metalloproteinase that plays a physiological role in the degradation of extracellular matrix found in skeletal tissues. It is synthesized as an inactive precursor that is activated by the proteolytic cleavage of its N-terminal propeptide.
Terms: Matrix Metalloproteinase 13 Preferred Term
Term UI T664485
Date01/18/2006
LexicalTag NON
ThesaurusID NLM (2007); Collagenase-3
Term UI T262205
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Matrix Metalloproteinase-13
Term UI T262206
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Collagenase 3
Term UI T262207
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); MMP-13 Metalloproteinase
Term UI T664574
Date01/18/2006
LexicalTag ABX
ThesaurusID NLM (2007); MMP13 Metalloproteinase
Term UI T664597
Date01/18/2006
LexicalTag ABX
ThesaurusID NLM (2007)

page delivered in 0.161s