MeSH Browser

MeSH Heading: Matrix Metalloproteinase 9
Tree Number(s): D08.811.277.656.300.480.205.360; D08.811.277.656.300.480.252.445; D08.811.277.656.300.480.525.700.350; D08.811.277.656.675.374.205.360; D08.811.277.656.675.374.252.445; D08.811.277.656.675.374.525.700.350; D12.776.467.836.350
Unique ID: D020780
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020780
Scope Note: An endopeptidase that is structurally similar to MATRIX METALLOPROTEINASE 2. It degrades GELATIN types I and V; COLLAGEN TYPE IV; and COLLAGEN TYPE V.
Entry Term(s): 92-kDa Gelatinase; 92-kDa Type IV Collagenase; Gelatinase B; MMP-9 Metalloproteinase; MMP9 Metalloproteinase; Matrix Metalloproteinase-9
Registry Numbers: EC 3.4.24.35
Previous Indexing: Collagenases (1989-1999)
Public MeSH Note: 2007; see GELATINASE B 2000-2006; MATRIX METALLOPROTEINASE 9 was indexed under COLLAGENASES 1989-1999
History Note: 2007(2000)
Entry Combination: antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Date Established: 2000/01/01
Date of Entry: 1999/11/08
Revision Date: 2021/05/21

Entry Combination: antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Metalloendopeptidases [D08.811.277.656.300.480]
        
        Collagenases [D08.811.277.656.300.480.205]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.300.480.205.351]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.300.480.205.352]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.300.480.205.358]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.300.480.205.360]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.300.480.205.363]
        
        Microbial Collagenase [D08.811.277.656.300.480.205.500]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Metalloendopeptidases [D08.811.277.656.300.480]
        
        Gelatinases [D08.811.277.656.300.480.252]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.300.480.252.420]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.300.480.252.445]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Metalloendopeptidases [D08.811.277.656.300.480]
        
        Matrix Metalloproteinases [D08.811.277.656.300.480.525]
        
        Matrix Metalloproteinases, Secreted [D08.811.277.656.300.480.525.700]
        
        Bone Morphogenetic Protein 1 [D08.811.277.656.300.480.525.700.049]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.300.480.525.700.100]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.300.480.525.700.150]
        
        Matrix Metalloproteinase 3 [D08.811.277.656.300.480.525.700.200]
        
        Matrix Metalloproteinase 7 [D08.811.277.656.300.480.525.700.250]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.300.480.525.700.300]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.300.480.525.700.350]
        
        Matrix Metalloproteinase 10 [D08.811.277.656.300.480.525.700.400]
        
        Matrix Metalloproteinase 11 [D08.811.277.656.300.480.525.700.450]
        
        Matrix Metalloproteinase 12 [D08.811.277.656.300.480.525.700.500]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.300.480.525.700.550]
        
        Matrix Metalloproteinase 20 [D08.811.277.656.300.480.525.700.800]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Metalloproteases [D08.811.277.656.675]
        
        Metalloendopeptidases [D08.811.277.656.675.374]
        
        Collagenases [D08.811.277.656.675.374.205]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.675.374.205.351]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.675.374.205.352]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.675.374.205.358]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.675.374.205.360]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.675.374.205.363]
        
        Microbial Collagenase [D08.811.277.656.675.374.205.500]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Metalloproteases [D08.811.277.656.675]
        
        Metalloendopeptidases [D08.811.277.656.675.374]
        
        Gelatinases [D08.811.277.656.675.374.252]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.675.374.252.420]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.675.374.252.445]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Metalloproteases [D08.811.277.656.675]
        
        Metalloendopeptidases [D08.811.277.656.675.374]
        
        Matrix Metalloproteinases [D08.811.277.656.675.374.525]
        
        Matrix Metalloproteinases, Secreted [D08.811.277.656.675.374.525.700]
        
        Matrix Metalloproteinase 1 [D08.811.277.656.675.374.525.700.100]
        
        Matrix Metalloproteinase 2 [D08.811.277.656.675.374.525.700.150]
        
        Matrix Metalloproteinase 3 [D08.811.277.656.675.374.525.700.200]
        
        Matrix Metalloproteinase 7 [D08.811.277.656.675.374.525.700.250]
        
        Matrix Metalloproteinase 8 [D08.811.277.656.675.374.525.700.300]
        
        Matrix Metalloproteinase 9 [D08.811.277.656.675.374.525.700.350]
        
        Matrix Metalloproteinase 10 [D08.811.277.656.675.374.525.700.400]
        
        Matrix Metalloproteinase 11 [D08.811.277.656.675.374.525.700.450]
        
        Matrix Metalloproteinase 12 [D08.811.277.656.675.374.525.700.500]
        
        Matrix Metalloproteinase 13 [D08.811.277.656.675.374.525.700.550]
        
        Matrix Metalloproteinase 20 [D08.811.277.656.675.374.525.700.800]
        
        Tolloid-Like Metalloproteinases [D08.811.277.656.675.374.525.700.900]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intercellular Signaling Peptides and Proteins [D12.776.467]
    - Matrix Metalloproteinases, Secreted [D12.776.467.836]

Matrix Metalloproteinase 9 Preferred

Concept UI: M0170326
Registry Numbers: EC 3.4.24.35
Scope Note: An endopeptidase that is structurally similar to MATRIX METALLOPROTEINASE 2. It degrades GELATIN types I and V; COLLAGEN TYPE IV; and COLLAGEN TYPE V.
Terms: Matrix Metalloproteinase 9 Preferred Term
Term UI T664556
Date01/18/2006
LexicalTag NON
ThesaurusID NLM (2007); 92-kDa Type IV Collagenase
Term UI T200321
Date10/12/1999
LexicalTag ABX
ThesaurusID NLM (2000); Matrix Metalloproteinase-9
Term UI T200327
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); 92-kDa Gelatinase
Term UI T200320
Date10/12/1999
LexicalTag ABX
ThesaurusID NLM (2000); MMP-9 Metalloproteinase
Term UI T664571
Date01/18/2006
LexicalTag ABX
ThesaurusID NLM (2007); MMP9 Metalloproteinase
Term UI T664585
Date01/18/2006
LexicalTag ABX
ThesaurusID NLM (2007); Gelatinase B
Term UI T200331
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000)

Matrix Metalloproteinase 9 MeSH Descriptor Data 2025