MeSH Browser

MeSH Heading: Renin
Tree Number(s): D08.811.277.656.074.500.780; D08.811.277.656.300.048.780; D08.811.277.656.837.750
Unique ID: D012083
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D012083
Annotation: do not confuse with RENNIN see CHYMOSIN
Scope Note: A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
Entry Term(s): Angiotensin-Forming Enzyme; Angiotensinogenase; Big Renin; Cryorenin; Inactive Renin; Pre-Prorenin; Preprorenin; Prorenin
Registry Numbers: EC 3.4.23.15; EC 3.4.23.-; EC 3.4.23.-
Related Numbers: 80965-96-4
Public MeSH Note: 1963; PRORENIN was listed under ENZYME PRECUSORS & RENIN 1977-2003; PREPRORENIN was listed under ENZYME PRECUSORS & RENIN 1980-2003
History Note: 1963; for PRORENIN use RENIN (NM) 1977-2003, for PREPRORENIN use RENIN (NM) 1980-2003
Date Established: 1963/01/01
Date of Entry: 1999/01/01
Revision Date: 2009/07/06

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0018776
Registry Numbers: EC 3.4.23.15
Related Numbers: 80965-96-4
Scope Note: A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
Terms: Renin Preferred Term
Term UI T035936
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1966); Angiotensinogenase
Term UI T035938
Date04/05/1990
LexicalTag NON
ThesaurusID NLM (1991); Angiotensin-Forming Enzyme
Term UI T035937
Date04/05/1990
LexicalTag NON
ThesaurusID NLM (1991)

Concept UI: M0061608
Registry Numbers: EC 3.4.23.-
Terms: Prorenin Preferred Term
Term UI T091611
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Big Renin
Term UI T091608
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Cryorenin
Term UI T091609
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Inactive Renin
Term UI T091610
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004)

Renin MeSH Descriptor Data 2024