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Zinc Finger E-box-Binding Homeobox 1 MeSH Descriptor Data 2025


MeSH Heading
Zinc Finger E-box-Binding Homeobox 1
Tree Number(s)
D12.776.260.400.906
D12.776.260.703.800
D12.776.930.780.945
Unique ID
D000071799
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071799
Scope Note
A transcription factor characterized by N-terminal and C-terminal CYS2-HIS2 ZINC FINGERS separated by a homeobox. It represses the expression of E-CADHERIN to induce the EPITHELIAL-MESENCHYMAL TRANSITION. It also represses PROTO-ONCOGENE PROTEINS C-BCL-6; regulates the cell type-specific expression of SODIUM-POTASSIUM-EXCHANGING ATPASE; and promotes neuronal differentiation.
Entry Term(s)
NIL-2-A Zinc Finger Protein
TCF8 Protein
Transcription Factor 8
Zeb1 Transcription Factor
Previous Indexing
Homeodomain Proteins (2004-2016)
Transcription Factors (2004-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/04/15
Zinc Finger E-box-Binding Homeobox 1 Preferred
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