A protein that binds to certain BONE MORPHOGENIC PROTEINS to regulate their activity. In Xenopus embryos, this is a dorsalizing factor localized to the SPEMANN ORGANIZER. Mutations in this protein may occur in NOG-RELATED-SYMPHALANGISM SPECTRUM DISORDER.
Registry Numbers
0
Public MeSH Note
2026; NOGGIN PROTEIN was indexed under CARRIER PROTEINS 2005-2025; and under PROTEINS 1992-2005
A protein that binds to certain BONE MORPHOGENIC PROTEINS to regulate their activity. In Xenopus embryos, this is a dorsalizing factor localized to the SPEMANN ORGANIZER. Mutations in this protein may occur in NOG-RELATED-SYMPHALANGISM SPECTRUM DISORDER.
