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Agouti-Related Protein MeSH Descriptor Data 2023


MeSH Heading
Agouti-Related Protein
Tree Number(s)
D12.644.276.074
D12.776.467.074
D23.529.074
Unique ID
D054369
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D054369
Scope Note
A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the HYPOTHALAMUS and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate food intake and body weight. Elevated AGRP has been associated with OBESITY.
Entry Term(s)
AGRP Protein
AGRT Protein
Registry Number
0
Previous Indexing
Intercellular Signaling Peptides and Proteins (1998-2007)
Receptors, Melanocortin (1997-2007)
Public MeSH Note
2008; AGOUTI-RELATED PROTEIN was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 1997-2007
History Note
2008 (1997)
Date Established
2008/01/01
Date of Entry
2007/07/09
Agouti-Related Protein Preferred
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